Cardiovascular Drugs 4 Flashcards

1
Q

What is heart failure? What are the symptoms?

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2
Q

What are the risk factors of heart failure?

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3
Q

Contrast systolic & diastolic heart failure

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4
Q

What is congestive heart failure?

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5
Q

What are the roles of compensatory mechanisms in heart failure?

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6
Q

What are the compensatory physiological responses for heart failure?

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7
Q

Describe the pathophysiology of cardiac performance

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8
Q

What is preload? What happens when it’s too high?

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9
Q

What is afterload?

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10
Q

How do factors on cardiac performance?

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11
Q

What are the therapeutic strategies of heart failure ?

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12
Q

What are the lifestyle modifications of heart failure?

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13
Q

What are the NYHA classes?

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14
Q

What are the revised classifications classification of HF According to AHA?

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15
Q

What is the recommended therapy by stage of CHF?

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16
Q

What are the drugs used to treat systolic HF?

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17
Q

Whhats the importance of ARN Inhibitors?

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18
Q

What are the clinical applications of ARN inhibitors ?

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19
Q

How is natriuretic peptide broken down?

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20
Q

What’s the mechanism of action in ARN inhibitors?

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21
Q

How do we monitor HF during ARNI treatment?

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22
Q

What are the adverse effects of ARN inhibitors?

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23
Q

What are the contraindications of ARNIs?

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24
Q

How can ACE inhibitors be used for HF?

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25
Q

What are the clinical applications in HF?

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26
Q

When are ARBS help with heart failure?

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27
Q

How do diuretics help with HF?

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28
Q

What are the clinical applications of diuretics?

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29
Q

What the role of spironolactone in HF?

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30
Q

What are the adverse effects of Spironolactone?

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31
Q

How are B-blockers helpful in treating heart failure?

A
32
Q

What are the clinical applications of B-blockers?

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33
Q

What drugs are used to treat systolic heart failure?

A
34
Q

What are direct vasodilators ?

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35
Q

What are the clinical applications of direct vasodilators for HF?

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36
Q

What’s the use of SGLT 2 inhibitors in HF?

A
37
Q

What’s the mechanism for SGLT2 inhibitors treating heart failure?

A
38
Q

What are the adverse effects of SGLT2 inhibitors?

A

Dapagliflozin

39
Q

What are inotropic agents?

A
40
Q

What are the disadvantages of Digoxin?

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41
Q

What is the mechanism of action of Digoxin?

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42
Q

How does digoxin lower Ca2+?

A
43
Q

What are the effects of digoxin a result of?

A
44
Q

What are the clinical applications of digoxin?

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45
Q

What is the PK of the digoxin?

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46
Q

What are the adverse effects of digoxin?

A
47
Q

What are the interactions of digoxin?

A
48
Q

What factors predispose digoxin toxicity?

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49
Q

What drugs predispose one to digoxin toxicity?

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50
Q

How do we treat digoxin?

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51
Q

What are the symptoms 9f severe digoxin intoxication?

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52
Q

What are the contraindications of digoxin?

A
53
Q

What’s the purpose of soluble guanylate cyclase stimulator?

A
54
Q

What’s the mechanism of action of Vericiguat?

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55
Q

What are the adverse effects of Vericiguat?

A
56
Q

How do If channel inhibitor treat heart rate?

A
57
Q

What are the adverse effects of Ivabradine?

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58
Q

What are the contraindications of Ivabradine?

A
59
Q

What are the primary & secondary treatments of HF?

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60
Q

What are the treatment guidelines for heart failure?

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61
Q

What drugs are to treat diastolic heart failure?

A
62
Q

How does diastolic heart failure respond to treatment?

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63
Q

How can diastolic heart failure be treated with diuretics?

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64
Q

Can ACEI/ARBs be used to treat diastolic HF?

A
65
Q

How can Calcium-channel blockers be used to treat Diastolic HF?

A
66
Q

How are B-blockers used to treat Diastolic HF?

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67
Q

What agents aren’t used to treat diastolic HF?

A
68
Q

What’s the use of PDE III inhibitors are used to treat acute heart failure?

A
69
Q

How is dopamine is used to treat acute heart failure?

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70
Q

How can dobutamine be used to treat acute heart failure?

A
71
Q

How can glucagon be used to treat heart failure?

A
72
Q

What inotropic agents are used to treat acute heart failure?

A

PDE III inhibitors, dopamine, dobutamine, and glucagon