Pharmacoepidemiology

Question 1

Two types of confounders

Answer 1

1. Measured
2. Unmeasured

Question 2

Safety, Comparative effectiveness (practical), Utilization, adherence, risk management, and pharmacovigilance are fall under the umbrella term of _______

Answer 2

Pharmaco-epidemiology

Question 3

Pharmacoepidemiology is Population-based research to produce clinical evidence on what three things?

Answer 3

1. Safety
2. Comparative effectiveness
3. Utilization and Adherence

Question 4

Efficacy vs Effectiveness

Answer 4

Efficacy= Ideal situation

Effectiveness=Real world

Question 5

Restriction matching, Standardization, stratification, Multivariate regression, and marginal structural models are all solutions to solve _____ confounders

Answer 5

Measured

Question 6

Small sample sizes, short follow-ups, non-representative patients, and intention to treat analysis are all flaws of _____ Trials

Answer 6

Pre-market (phase 3)

Question 7

2-stage sample, Imputation, propensity score calibration are all solutions to ____ confounders that are _____ _____

Answer 7

Unmeasured, measured in substudy

Question 8

Explanatory randomized control trials are great for _____ validity, whereas Observational studies lend themselves greater power to determine _____ validity.

Answer 8

Internal, External

Question 9

The inability to track Rate of adverse events in drugs, effect size, delayed effects, or small risks is a limitation of _____ reporting

Answer 9

Spontaneous (quick)

Question 10

Cross-over, Active choice of comparison group, and Instrumental variables are all solutions to ______ confounders

Answer 10

Unmeasurable