Clinical Decision Making Flashcards
Dr. Willet
Two types of studies best for examining rare disease/side-effects
- Pharmacoepidem
- Case-control
There are two studies to best answer Diagnoses; if there is a “follow-up”, then you would want to use a ______ study
Large prospective Cohort
Treatment Threshold question for Clinical-decision making
Post-test prob to be comfortable to treat (more toxic means higher)
Retrospective cohort studies are good for _____ ___
Hypothesis generating
Testing Threshold question for Clinical-decision making
Post-test prob to be comfortable not treating pt. (More serious means lower)
There are two studies to best answer Diagnoses; if there are multiple Reference Standard Testing, then you would want to use a ______ study
Cross-sectional
Best study for prognosis?
Cohort study
What is a useless LR?
1
Best study for showing improved mortality?
RCT
A perfect LR+ is _____, whereas a perfect LR- is _____
>10, <0.1
Instead of RCT, you might have to choose a prospective cohort if _____ _____
Harmful treatment
LR- formula and verbal explanation
Chance of - test in diseased
Chance of - test in normal
(1-sensitivity)/specificity
Name 3 studies better than RCTS (least to most best)
- Critical Article Synopsis
- Critical Topic Synthesis
- Systematic Reviews
LR+ formula and verbal explanation
Chance of + test in diseased
Chance of + test in normal
Sensitivity/ (1- specificity)