Pharmacodynamics: Lecture 7 Flashcards
1
Q
What are the types of G-coupled protein receptors?
A
Muscuranic
Adrenoreceptors
Histaminergic receptors
2
Q
What are the effectors of G-coupled receptors?
A
Adenyl cyclase, CAMP
IP3, DAG
3
Q
Tyrosine kinases are involved in what??
A
Malignancies
4
Q
Which drugs act of the tryosine kinases to prevent formation of new growths?
A
Imanitib and Erlotinib
5
Q
What causes the desensitisation of G-coupled protein receptors?
A
Phosphorylation
6
Q
What is the function of the enzyme phosphotase?
A
It functions to reverse the action of kinases by breaking down phosphates
