Pharmacodynamics Flashcards
1
Q
What is pharmacodynamics?
A
- Action that a drug has on the body which could enhance or depress the physiological changes in the body
2
Q
What are the 4 types of regulatory proteins?
A
- Receptors
- Enzymes
- Carrier molecules
- Ion channels
3
Q
How do drugs bind to receptors?
A
- Key and lock method
4
Q
What is an agonist?
A
- Activate the receptor
- Good affinity and efficacy
5
Q
What is an antagonist?
A
- Bind to receptors but block the effects of what an agonist would do
- Poor affinity and efficacy
6
Q
What is affinity?
A
- Ability of a drug to bind with a receptor
7
Q
What is efficacy?
A
- Ability of a drug to produce the desired effect
8
Q
What are the 7 receptor families?
A
- Adrenergic
- Cholinergic
- Dopaminergic
- Serotonergic
- GABA-ergic
- Glutamatergic
- Opiodergic
9
Q
What is the therapeutic effect?
A
- Effect of drug to control a specific disease or management of physiological function
10
Q
What is maximum safe concentration (MSC) / minimum toxic concentration (MTC)?
A
- Dosage is too high and may cause a toxic effect
11
Q
What is minimum effective concentration (MEC)?
A
- Dosage is too low and this prevents the desired therapeutic effect
