PHARMACODYNAMICS

Question 1

“what a drug does to
the body”

Answer 1

PHARMACODYNAMICS

Question 1

All but a small number of
drugs interact with specific
sites called?

Answer 1

receptors.

Question 1

bind
to the receptor and prevent the
cell from producing an effect.
–May block the action of another drug.

Answer 1

Antagonists (blockers)

Question 2

a selective beta-blocker
blocks beta- 1 receptors in the heart,
reducing the heart rate;

Answer 2

Propranolol

Question 2

blocks H-2 (histamine)
receptors in the gastrointestinal tract,
reducing gastric acid and promoting
healing of duodenal and gastric ulcers.

Answer 2

Ranitidine

Question 2

bind to
the receptor on the cell membrane
and act on the cell through the
receptor to produce a
pharmacologic effect.

Answer 2

Agonists (activators)

Question 3

blocks alpha-1 receptors in
blood vessels, producing vasodilation.
Used in treatment of hypertension.

Answer 3

Doxazosin

Question 3

binds to and activates beta-2 receptors in the
bronchiolar smooth muscles,
producing bronchodilation / for asthma

Answer 3

Salbutamol

Question 4

stimulates alpha-2 receptors
in the brain stem, thus reducing the
sympathetic nervous system outflow.
Used in hypertension.

Answer 4

Clonidine

Question 5

for bradychardia // blocks the effect of acetylcholine, causes drymouth

Answer 5

Atropine

Question 6

is used in the treatment of dementia
to increase levels of acetylcholine in the brain.

Answer 6

Galantamine

Question 7

drugs are strong anti-emetics

Answer 7

5-HT antagonists,

Question 8

The ability of a drug to produce a
response when it binds to a receptor

Answer 8

Potency

Question 9

The ability of a drug to produce a
response when it binds to a receptor

Answer 9

Efficacy

Question 10

The ability of a drug to combine with one
particular type of receptor. Examples of
receptors: acetylcholine, histamine and
adrenoreceptors.

Answer 10

Specificity

Question 11

The relationship between a drug’s
desired therapeutic effects and its
adverse effects (margin of safety)

Answer 11

Therapeutic Index

Question 12

the action of one
drug is increased by the
presence of a second drug

Answer 12

*Potentiation, or synergy

Question 13

occurs when the action of
one drug reduces or blocks
the effect of a second.

Answer 13

antagonistic effect

Question 14

Factor indicating that the
use of a particular drug
will cause harm.

Answer 14

Contraindications

Question 15

expected effect
that may or may not cause harm.

Answer 15

Side effects

Question 16

Harmful
and unexpected. It may be
seen as an effect in any organ.

Answer 16

Adverse effects

Question 17

The ability of a drug to attack only
those systems found in foreign
cells i

Answer 17

selective
toxicity.

Question 18

occurs
when the body recognizes the
drug as foreign and responds
by histamine release.

Answer 18

allergic reaction

Question 19

a decision-making,
problem-solving process—to provide efficient
and effective care.

Answer 19

*nursing process

Question 20

Pregnancy and Lactation
Labeling Final Rule (PLLR) went
into effect on June 30, 2015

Answer 20

Pregnancy and Lactation
Labeling Final Rule (PLLR) went
into effect on June 30, 2015

Question 21

drip
method

Answer 21

direct bolus method

Question 22

Injection Sites
ventral forearm, upper chest,
shoulder.

Answer 22

Intradermal:

Question 23

Injection Sites
outer aspects of the arms and thighs, hip
and lower abdomen, above the iliac crest.

Answer 23

Sc:

Question 24

Injection Sites
ventrogluteal, deltoid, dorsogluteal,
vastus lateralis, rectus femoris

Answer 24

IM:

Question 25

Injection Sites
an IM technique used for solutions
that are especially staining or irritating.

Answer 25

*Z-track

Question 26

Injection Sites
lower arm and hand, upper arm,
antecubital fossa

Answer 26

IV