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S2 Case 4 - Hypertension Monitoring > Pharmaceutics - Packaging > Flashcards

Pharmaceutics - Packaging Flashcards

1
Q

What are the 2 types of packaging?

A

Primary
Secondary

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2
Q

What is primary packaging?

A

Direct contact with the medicine

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3
Q

What does the primary packaging do?

A

Protect medicine from damage + contaminations

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4
Q

What is secondary packaging?

A

Do not make direct contact with the medicine

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5
Q

What are the different types of primary packaging?

A

Single/multi-dose container
Strip packs
Blister packs
Glass vials + ampoules
Sachets, tubes, bags + pre-filled syringed

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6
Q

What must a primary pack offer?

A

Child-resistance
Tamper-resistance + tamper evident

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7
Q

What do closures provide?

A

Effective seal to retain the contents + exclude external contaminants

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8
Q

What is the main problem with plastic?

A

Contain low-molecular weight additives that can be released over time

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9
Q

Why is glass still used today?

A

Inert
Excellent barrier properties
Stable
Clear = can see content
Coloured to protect from UV

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10
Q

What are the different types of glass?

A

Type I, II + III

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11
Q

What is Type I also called?

A

Borosilicate glass

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12
Q

What is Type I produced by?

A

Addition of boric oxide to glass

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13
Q

What are the advantages of Type I glass?

A

Highest pharmaceutical grade
Most inert
High thermal resistance
Suitable for all drug preparations

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14
Q

What is the problem with Type I glass?

A

Expensive

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15
Q

What is Type II glass called?

A

Soda-lime-silica glass

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16
Q

How is Type II glass made?

A

Treated with sulphur dioxide

17
Q

What is Type II used for?

A

Packaging aqueous preparations
eg. eye preparations + dropper bottles

18
Q

What is Type III glass made from?

A

Soda-lime-silica glass

19
Q

What is Type III suitable for?

A

Non-parenteral preparations + powders for injections

20
Q

What is Type III commonly used to produce?

A

Dispensary medical bottles

21
Q

How are plastics produced?

A

Macromolecules produced either synthetically or by alteration of natural resin

22
Q

What are the advantages of plastics?

A

Light + shatterproof
Clear
Easily sealed + shaped
Cheap
Greater versality

23
Q

What are the disadvantages of plastics?

A

Chemical inertness + permeability lower than Type I glass
Less resistant to heat + light
Undergo cracking
Leach into content

24
Q

What are the advantages of metals?

A

Mechanical strong
Shatterproof
Lightweight
Impermeable to light, moisture + gases
Malleable

25
Q

What are the disadvantages of metals?

A

More expensive
React with product

26
Q

What are metals used for?

A

Packaging for non-parenteral administration

27
Q

What is metal prone to?

A

Corrosion due to interaction with H2O + O

28
Q

What is rubber used for?

A

Closures/stoppers

29
Q

What do closures on parenteral containers do?

A

Allows needle to enter + reseal when needle is removed

30
Q

What is paper used for?

A

Labels + leaflets
Carton boxes
Bags
Sachets

31
Q

What are the advantages of paper?

A

Low cost
Non-toxic
Recyclable

32
Q

What are the disadvantages of paper?

A

Has no barrier properties

S2 Case 4 - Hypertension Monitoring (12 decks)

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