Pharma- Toxicities and Drugs Flashcards

1
Q

Agranulocytosis

A

Carbamazepine, clozapine

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2
Q

Aplastic anemia

A

Chloramphenicol

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3
Q

Cyanide accumulation

A

Nitroprusside

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4
Q

Cycloplegia

A

Antimuscarinics

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5
Q

Date rape

A

Rohypnol (Flunitrazepam)

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6
Q

Diabetes insipidus (nephrogenic)

A

Lithium

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7
Q

Ebstein�s anomaly

A

Lithium (in pregnancy; disputed)

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8
Q

Endometrial CA

A

Estrogen HRT (prevent by combining with progestin)

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9
Q

Fanconi�s syndrome

A

Expired Tetracyclines

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10
Q

�First-dose� syncope

A

Prazosin

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11
Q

Gingival hyperplasia

A

Phenytoin

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12
Q

Gray baby syndrome

A

Chloramphenicol

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13
Q

Monday disease

A

Nitrates

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14
Q

Serotonin syndrome

A

MAOI and SSRI/Tyramine/Sympathomimetics; muscle rigidity, myoclonus, hyperthermia, CVS instability, seizures (also TCAs, dextrometorphan, meperidine, MDMA, St. John�s wort)

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15
Q

Serum sickness

A

Cefaclor

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16
Q

Livor reticularis

A

Amantadine

17
Q

Lupus-like syndrome

A

Hydralazine, INH, Procainamide, Phenytoin (HIPP)

18
Q

Methemoglobinemia

A

Nitrites (not nitrates)

19
Q

Photosensitivity

A

Sulfonamides, Amiodarone, Tetracycline (SAT)

20
Q

Pseudomembranous colitis

A

Clindamycin, Ampicillin

21
Q

Pseudotumor cerebri

A

Tetracycline

22
Q

Pulmonary fibrosis

A

Amiodarone, Bleomycin, Busulfan

23
Q

Reye syndrome

A

Aspirin (in children)

24
Q

Thyrotoxicosis

A

Amiodarone

25
Q

Acute mesenteric ischemia (SMA occlusion)

A

Digitalis

26
Q

Vaginal Clear Cell CA (in daughters)

A

Diethylstilbestrol

27
Q

Vertical and horizontal nystagmus

A

PCP (by extension, Ketamine)

28
Q

Yellow vision

A

Digitalis