Pharma- indications and MOA Flashcards

1
Q

Active against PRSPs

A

Ceftriaxone, cefotaxime

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2
Q

ADH antagonist tetracycline

A

Demeclocycline

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3
Q

AML M3 treatment

A

Retinoic acid

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4
Q

Anaerobes above the diaphragm

A

Clindamycin (static, 50S)

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5
Q

Anaerobes below the diaphragm

A

Metronidazole (disulfiram rxn, metallic taste)

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6
Q

Anti-liver schizonts

A

Primaquine

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7
Q

Anti-sense DNA (for CMV)

A

Fomivirsin

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8
Q

Atypical antipsychotic

A

Clozapine (D4 and 5-HT2 selective), Olanzapine (5-HT2)

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9
Q

AV nodal arrhythmias

A

Adenosine

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10
Q

Biliary excretion (beta-lactams)

A

Cefoperazone, Ceftriaxone, Nafcillin

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11
Q

Cestodes

A

Praziquantel and niclosamide

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12
Q

Chagas disease

A

Nifurtimox

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13
Q

Chronic heart failure

A

Labetalol, carvedilol, metoprolol

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14
Q

Chronic Myelogenous Leukemia

A

Imatinib (Gleevec)

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15
Q

Claudication

A

Cilostazol

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16
Q

CMV retinitis

A

Ganciclovir

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17
Q

Cysticercosis

A

Albendazole, praziquantel

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18
Q

Decreases post-op ileus

A

Erythromycin, Ketorolac

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19
Q

Depletes magnesium

A

Amphotericin, AGs, Foscarnet, Cisplatin, Ifosfamide

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20
Q

Derma steroid of choice (oral)

A

Prednisone

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21
Q

Not dialyzable

A

Amphotericin B, cefonicid, cefoperazone, ceftriaxone, erythromycin, nafcillin, tetracycline, vancomycin

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22
Q

Disulfiram-like reaction

A

Metronidazole, TMP-SMX, cefotetan, cefoperazone, cefamandone, 1st-gen sulfonylureas

23
Q

Dissociative anesthesia

A

Ketamine

24
Q

Elective bowel surgery

A

Neomycin and erythromycin

25
Q

Eschar treatment

A

Mafenide acetate

26
Q

Exacerbate psoriasis

A

Beta-blockers, lithium, ACE inhibitors

27
Q

Gynecomastia

A

Spironolactone, Digitalis, Cimetidine, Alcohol, Ketoconazole, Furosemide, Diazepam, Verapamil, MJ

28
Q

Hydatid disease

A

Albendazole

29
Q

Iodine-containing antiarrhythmic

A

Amiodarone

30
Q

Increase insulin secretion

A

B2 agonists

31
Q

Increase renin secretion

A

B1 agonists

32
Q

Leishmaniasis

A

Sodium stibogluconate

33
Q

Longest-acting B-blocker

A

Nadolol

34
Q

Mast cell degranulation blocker

A

Cromolyn sodium

35
Q

Mountain sickness

A

Acetazolamide

36
Q

Myasthenia gravis diagnosis

A

Edrophonium

37
Q

Nephrotoxic agent used in surgery

A

Furosemide (also AGs, vanco)

38
Q

Neutropenic nadir post-chemotherapy

A

7-10 days

39
Q

Onchocerciasis (river blindness)

A

Ivermectin

40
Q

Opioid with minimal histamine release

A

Fentanyl, remifentanil

41
Q

Parenteral NSAID

A

Ketorolac

42
Q

Partial _-agonists

A

Labetalol, pindolol, acebutolol

43
Q

Pneumocystis pneumonia

A

TMP-SMX

44
Q

Poxvirus inhibitor

A

Methisazone

45
Q

Quinine-resistant malaria

A

Artemesins (artesunate, artemether)

46
Q

[Most] S phase specific antimetabolite

A

Cytarabine

47
Q

Sildenafil interaction

A

Nitrates (may cause hypotension)

48
Q

�Stage-fright�

A

Propranolol

49
Q

Tamoxifen optimum treatment time

A

5 years

50
Q

TCA with H1/H2 blocking actions

A

Doxepin

51
Q

Thrombolytic toxicity (antidote)

A

Aminocaproic acid

52
Q

Topical steroid for face and intertriginous areas

A

Hydrocortisone acetate (low-potency)

53
Q

Urge incontinence

A

Oxybutyrin, metaproterenol

54
Q

Wolff-Parkinson-White syndrome

A

Amiodarone, Flecainide