Pharm7 Flashcards
Direct Sympathomimetics.
Epinephrine Norepinephrine Isoproterenol Dopamine Dobutamine Phenylephrine Albuterol,Salmeterol,Terbutaline Ritodrine
Indirect Sympathomimetics.
Amphetamine
Ephedrine
Cocaine
a1: +++
a2: +++
ß1: ++++
ß2: ++++
D1: 0
Epinephrine
a1: ++++
a2: ++++
ß1: ++
ß2: 0
D1: 0
Norepinephrine
a1: 0
a2: 0
ß1: ++++
ß2: ++++
D1: 0
Isoproterenol
a1: +++
a2: +++
ß1: +++
ß2: ++
D1: +++
Dopamine
a1: +
a2: +
ß1: ++++
ß2: +
D1: 0
Dobutamine
a1: +++
a2: ++
ß1: 0
ß2: 0
D1: 0
Phenylephrine
a1: 0
a2: 0
ß1: ++
ß2: ++++
D1: 0
Albuterol
Salmeterol
Terbutaline
a1: 0
a2: 0
ß1: 0
ß2: ++++
D1: 0
Ritodrine
Releases stored catecholamines.
Amphetamine
Ephedrine
Reuptake inhibitor
Cocaine
Treatment for:
- Anaphylaxis
- Asthma
- Hypotension
- Glaucoma (open-angle)
Epinephrine
Treatment for:
- Hypotension (Decreased renal perfusion)
Norepinephrine
Treatment for:
- Torsades de Pointes (tachycardia decreases QT interval)
- Bradyarrhythmias (can worsen ischemia)
Isoproterenol
Treatment for:
- Shock (renal perfusion)
- Heart failure; inotropic & chronotropic
Dopamine
Treatment for:
- Heart failure
- Stress testing; ionotropic & chronotropic
Dobutamine
Treatment for:
- Hypotension (vasoconstrictor)
- Ocular procedures (mydriatic)
- Rhinitis (decongestant)
Phenylephrine
Treatment for:
- Acute asthma
Albuterol
Metaproterenol
Treatment for:
- Long-term asthma
- COPD
Salmeterol
Treatment for:
- Reduce premature uterine contractions
Ritodrine (Terbutaline)
Treatment for:
- Narcolepsy
- Obesity
- ADD
Amphetamines
Treatment for:
- Nasal decongestant
- Urinary incontinence
- Hypotension
Ephedrine
Cocaine uses.
causes Vasoconstriction
Local anasthetic
What should you never give if cocaine intoxication is suspected?
ß-blockers
*can lead to unopposed a1 activation and extreme hypertension
