Pharm10 Flashcards

Toxin - Antidotes/Treatment

1
Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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2
Q

Salicylates

A

NaHCO3 (alkalinize urine)

Dialysis

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3
Q

Amphetamines (basic)

A

NH4Cl (acidify urine)

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4
Q

Acetylcholinesterase Inhbitors, Organophosphates

A

Atropine, Pralidoxime

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5
Q

Antimuscarinic, Anticholinergic agents

A

Physostigmine salicylate

Control hyperthermia

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6
Q

ß-blockers

A

Glucagon

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7
Q

Digitalis

A

“KLAM”

Normalize K+
Lidocaine
Anti-dig Fab fragments
Mg++

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8
Q

Iron

A

Deferoxamine

Deferasirox

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9
Q

Lead

A

CaEDTA
Dimercaprol
Succimer
Penicillamine

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10
Q

Mercury, Arsenic Gold

A

Dimercaprol (BAL)

Succimer

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11
Q

Copper, Arsenic, Gold

A

Penicillamine

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12
Q

Cyanide

A

Nitrite + Thiosulfate

Hydroxocobalamin

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13
Q

Methemeglobin

A

Methylene blue

Vitamin C

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14
Q

Carbon Monoxide

A

100% O2

Hyperbaric O2

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15
Q

Methanol, Ethylene glycol (antifreeze)

A

Fomepizole > ethanol

Dialysis

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16
Q

Opiods

A

Naloxone/Naltrexone

17
Q

Benzodiazepines

A

Flumazenil

18
Q

TCAs

A

NaHCO3 (plasma alkalinization)

19
Q

Heparin

A

Protamine

20
Q

Warfarin

A

Vitamin K

Fresh Frozen Plasma

21
Q

tPA, Streptokinase, Urokinase

A

Aminocaproic acid

22
Q

Theophylline

A

ß-blocker