Pharm6 Flashcards
Muscarinic Antagonists. (9)
Atropine Homatropine Tropicamide Benztropine Scopolamine Ipratropium tiotopium Oxybutynin Glycopyrrolate
Atropine, Homatropine, Tropicamide
Eye
Produces mydriasis and cycloplegia
Benztropine
CNS
Parkinson’s disease
Scopolamine
CNS
Motion sickness
Ipratropium, tiotropium
Respiratory
COPD
Asthma
Oxybutynin
Genitourinary
Reduces urgecy in milde cystitis
Reduces bladder spasms
Cyclopyrrolate
Gastrointestinal & Respiratory
Parenteral: Preoperative to reduce airway secretions
Oral: Drooling, peptic ulcer
Muscarinic antagonist used to treat bradycardia and opthalmic applications.
Atropine
Atropine:
- Eye
INcreased pupil dilation
Cycloplegia
Atropine:
- Airway
DEcreased secretions
Atropine:
- Stomach
DEcreased acid secretion
Atropine:
- Gut
DEcreased motility
Atropine:
- Bladder
DEcreased urgency in cystitis
S/S of Atropine Toxicity.
HOT as a hare DRY as a bone RED as a beet BLIND as a bat MAD as a hatter