Pharm4

Question 1

Sympathetic Receptor:

- a1

Answer 1

G-Protein Class: q

Question 2

Sympathetic Receptor:

- a2

Answer 2

G-Protein Class: i

Question 3

Sympathetic Receptor:

- ß1

Answer 3

G-Protein Class: s

Question 4

Sympathetic Receptor:

- ß2

Answer 4

G-Protein Class: s

Question 5

Parasympathetic receptor:

- M1

Answer 5

G-Protein Class: q

Question 6

Parasympathetic receptor:

- M2

Answer 6

G-Protein Class: i

Question 7

Parasympathetic receptor:

- M3

Answer 7

G-Protein Class: q

Question 8

Dopamine receptor:

- D1

Answer 8

G-Protein Class: s

Question 9

Dopamine receptor:

- D2

Answer 9

G-Protein Class: i

Question 10

Histamine receptor:

- H1

Answer 10

G-Protein Class: q

Question 11

Histamine receptor:

- H2

Answer 11

G-Protein Class: s

Question 12

Vasopressin receptor:

- V1

Answer 12

G-Protein Class: q

Question 13

Vasopressin receptor:

- V2

Answer 13

G-Protein Class: s

Question 14

Function:

- a1

Answer 14

INCREASED:

• vascular smooth muscle contraction
• pupillary dilator muscle contraction (mydriasis)
• intestinal & bladder sphincter contraction

Question 15

Function:

- a2

Answer 15

DECREASED:

• sympathetic outflow
• insulin release
• lipolysis

INCREASED:
- platelet aggregation

Question 16

Function:

- ß1

Answer 16

INCREASED:

• heart rate
• contractility
• renin release
• lipolysis

Question 17

Function:

- ß2

Answer 17

Vasodilation
Bronchodilation
Ciliary muscle relaxation
INCREASED:
 - heart rate
 - contraction
 - lipolysis
 - insulin release
 - aqueous humor production
DECREASED:
 - uterine tone (tocolysis)

Question 18

Function:

- M1

Answer 18

CNS, enteric nervous system

Question 19

Function:

- M2

Answer 19

DECREASED:

• heart rate
• contractility of Atria

Question 20

Function:

- M3

Answer 20

INCREASED:

• exocrine gland secretions
• gut peristalsis
• bladder contraction
• bronchoconstriction
• pupillary sphincter muscle contraction (miosis)
• ciliary muscle contraction (accomodation)

Question 21

Function:

- D1

Answer 21

Relaxes renal vascular smooth muscle

Question 22

Function:

- D2

Answer 22

Modulates transmitter release, especially in brain

Question 23

Function:

- H1

Answer 23

Contraction of bronchioles
Pruritis
Pain
INCREASED:
 - nasal & bronchial mucus production

Question 24

Function:

- H2

Answer 24

INCREASED:

- gastric acid secretion

Question 25

Function:

- V1

Answer 25

INCREASED:

- vascular smooth muscle contration

Question 26

Function:

- V2

Answer 26

INCREASED:
- H20 permeability and reabsorption in the Collecting tubules of kidney

“V2 is found in the 2 kidneys”