Pharm: Tobacco, Vaping, Medical Marijuana, CBD Flashcards
What are some general “benefits” of vaping over traditional cigarettes?
less expensive
tastes better
whiter teeth/better skin
senses of smell and taste improve
better socially
less lung damage
can help with cessation
What is the demographic data for vaping in the US?
19% girls
23% of boys
>3.6 million teens use Vapes
More common in older white and non-hispanic teens
May use flavors or use both e-cigs and traditional cigs
Why is vaping so enticing to younger audiences?
may be used by family members
tastes good
safer
targeted marketing
What is the main concern of vaping in youths?
nicotine can harm developing brains (up to age 25)
can cause them to start using cigarettes or former smokers can become re-addicted to nicotine via vaping
What is the function of the PFC?
Executive function such as
conflicts
good v. bad. v. best
consequences/outcomes
motivation
Nicotine interferes with which function of the brain thus leading to impaired PFC?
neuroplasticity
this leads to alterations in gene expression, cell structure, signaling, pruning, and myelination
In rat studies, what whas the result of nicotine administration on the adolescent brain?
long term cognitive impairment
decreased memory and attention
behavioral disturbances later in life
Vaping of cannabinoid products/Vitamin E acetate seeming lead to what outcome?
acute toxic injury manifesting as pneumonia, pneumonitis, alveolar damage/hemorrhage or ARDS
most seriously ill patients developed extensive lung damage, required ventilation, and had permanent lung damage
The likely cause of critical lung disease or deaths due to vaping was due to the following:
Vit. E acetate
contaminants
“not detected”/unknown cause
internet recipe/DIYs
Tarrifs/”knock-offs”
slow regulations by FDA
What are some regulations in place to inhibit youths from vaping?
federal minimum age for purchasing tobacoo products is now 21
sale of fruit and mint cartridges is discontinued (except for tank vaping systems)
In Missouri, how can one obtain medical marijuana?
Step 1: Obtain ID card ($25)
Step 2: Have a qualifying condition
Step 3: Hit up your local ReLeaf
What is the MOA of Dronabinol?
What are the effects?
synthetic delta-9-THC
affinity for CB1>CB2
causes analgesia, appetite enhancement, muscle relaxation, hormonal actions, euphoria, floaty-feeling, memory lapses
What are the indications for Dronabinol?
Indications for Nabilone?
anorexia in AIDS patients, chemo induced n/v
OSA (off label)
Chemo induced n/v
What are the adverse effects of Dronabinol?
decreased judgement/coordination
sedation, red eyes, depression, dizziness, tachycardia, hypotension, hallucinations, dry mouth
What are the adverse effects of Dronabinol in youths?
adverse effects on intelligence and metnal function
