Pharm- Thyroid Flashcards

1
Q

Beta blockers- Indications

A

Adjuvant for hyperthyroid- protect heart from CV risks

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2
Q

Beta blockers- MOA

A

Blocks beta 1 & beta 2 adrenergic stimulation

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3
Q

Beta blockers- AE

A

Weakness, fatigue, constripation, N/V/D

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4
Q

CCB- Indications

A
  • Adjuvant for hyperthyroid when propranolol contraindicated
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5
Q

CCB- MOA

A
  • Inhibits CA from entering channels
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6
Q

CCB- AE

A

Edema, dizziness, gout, AV block

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7
Q

Propythiaouracil- Indicaitons

A

Hyperthyroidism- adjunctive

- DOC for pregnancy

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8
Q

Propythiaouracil- MOA

A
  • Inhibits thyroid hormone synthesis by blocking iodine oxidation in thyroid
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9
Q

Propythiaouracil- AE

A

Rash, alopecia, pruritis

BBW: liver injury/ failure

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10
Q

Liotrix- Indications

A

Hypothyroid, synthetic mix of T4 & T3

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11
Q

Liotrix- MOA

A
  • Syntethic compound of T3 & T4 hormones
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12
Q

Liotrix- AE

A

BBW: Euthyroid, life threatening toxic effects

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13
Q

Levothyroxine- Indications

A

Gold standard for hypothyroid

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14
Q

Levothyroxine- MOA

A

Synthetic T4

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15
Q

Levothyroxine- AE

A

Cardiac, anxiety, wt loss, decreased bone density

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16
Q

Methimazole- Indications

A

Hyperthyroid

- Preferred over Propythiaouracil

17
Q

Methimazole- MOA

A

Inhibits thyroid hormone synthesis

18
Q

Methimazole- AE

A

Rash, edema, hepatic impairment