Pharm- Thyroid Flashcards
Beta blockers- Indications
Adjuvant for hyperthyroid- protect heart from CV risks
Beta blockers- MOA
Blocks beta 1 & beta 2 adrenergic stimulation
Beta blockers- AE
Weakness, fatigue, constripation, N/V/D
CCB- Indications
- Adjuvant for hyperthyroid when propranolol contraindicated
CCB- MOA
- Inhibits CA from entering channels
CCB- AE
Edema, dizziness, gout, AV block
Propythiaouracil- Indicaitons
Hyperthyroidism- adjunctive
- DOC for pregnancy
Propythiaouracil- MOA
- Inhibits thyroid hormone synthesis by blocking iodine oxidation in thyroid
Propythiaouracil- AE
Rash, alopecia, pruritis
BBW: liver injury/ failure
Liotrix- Indications
Hypothyroid, synthetic mix of T4 & T3
Liotrix- MOA
- Syntethic compound of T3 & T4 hormones
Liotrix- AE
BBW: Euthyroid, life threatening toxic effects
Levothyroxine- Indications
Gold standard for hypothyroid
Levothyroxine- MOA
Synthetic T4
Levothyroxine- AE
Cardiac, anxiety, wt loss, decreased bone density