Labs Flashcards
1
Q
Free T4 (thyroxine)
A
- Most accurate reflection of thyrometabolic status
- Difficult to measure
- Assessed in confounding non thyroidal illnesses
2
Q
Total serum T4 (Throxine )
A
- Initial screening test to assess thyroid fxn
- High in hyper, low in hypo
- Measures free & bound
3
Q
Serum T3 (Triiodothyronine) resin uptake
A
- Thyroid hormone binding ratio
- Indicates number of binding sites on thyroid binding protein
- Low when concentration of of thyroid binding protein is high
- Radiolabeled T3
4
Q
Total serum T3 Triiodothyronine
A
- Indicator of hyperthyroid
- Low in malnutrition, cirrhosis & uremia
5
Q
Thyroid stimulating hormone
A
- Measure response to levothyroxine tx
- Elevated in hypothyroid, decreased in hyperthyroid
- Secreted from anterior pituitary
6
Q
Radioactive iodine uptake test
A
- Assessment of intrinsic fxn on thyroid gland
- Ability of thyroid to trap and concentrate iodine
- Distinguish hyperthyroid causes
- Hot spots in thyrotoxicosis, iodine deficiency
- Affected by store of iodine
7
Q
Antithyroid antibodies
A
- Hasimoto & Graves disease
- Not necessary for dx
8
Q
Follicle stimulating hormone
A
- Increases in puberty prior to LH
- Distinguish primary versus secondary gonadal sufficiency
- Increased in menopause, ovarian failure
- Decreased in adenomas, ovarian tumors
9
Q
Luteinizing hormone
A
- Surge causes ovulation
- Increased in ovarian failure menopause
- Decreased: pituitary adenomas, and eating disorders
10
Q
Estradiol
A
- Evaluation of menstrual and fertility
- Estriol elevated in pregnancy
- Estradiol elevated tumors, menstruation, pregnancy and ovulation
11
Q
Testosterone
A
- Elevated with female virilization, adrenal neoplasms, hirsutism, adrenal hyperplasia, ovarian tumors
- Draw early AM- at peak
- Decreased in hypogonadism in males
12
Q
Human chorionic gonadotropin
A
- Indication of pregnancy
- Tumors of ovaries, testies, gonads
13
Q
Thyroid autoantibodies
A
Elevated in graves and hashimotos disease
- Evidence of autoimmune disorders
14
Q
Serum thyroglobulin
A
- Precursor protein for thyroid protein synthesis
- Marker for thyroid cancer
- Elevated in overactive thyroid
15
Q
Antithyroperoxidase antibodies
A
- Elevated in Hashimoto (95%) & Graves and 10% with out thyroid disease
