Parathyroid disorders Flashcards

1
Q

Hypoparathyroidism- Eti

A
  • Acquired- thyroidectomy, damage due to heavy metals
  • Mg deficiency
  • Congenital
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2
Q

Hypoparathyroidism- Sx

A
  • Hypocalcemia (chovstek sign, trousseau)
  • Tetany, cramps, carpopedal spasm
  • AMS, irritability
  • Convulsions
  • Stridor
  • Blurry vision
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3
Q

Hypoparathyroidism- Dx

A
  • Low calcium, PTH

- High phosphate,

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4
Q

Hypoparathyroidism- Tx

A
  • Maintain serum calcium & vit D

- Teriparatide (PTH- Sub Q)

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5
Q

Pseudohypothyroidism- Eti

A
  • Renal resistance to PTH, congenital

- High PTH, hypocalcemia & hypophosphatemia

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6
Q

Pseudohypothyroidism- Sx

A
  • Short stature
  • Round face
  • Obesity
  • Short 4th metacarpal
  • Mental retardation
  • Ectopic bone formation
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7
Q

Hyperparathyroidism- Eti

A
  • Women, 7th decade
  • Most common cause of hypercalcemia,1-4 cases/ 1000
  • Primary (adenoma), renal failure
  • Mulitple endocrine neoplasias
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8
Q

Hyperparathyroidism- Sx

A
  • Hypercalcemia- stones, bones, abd groans, psych overtones
  • Fracture, cystic bone lesions
  • Bone pain & arthralgia
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9
Q

Hyperparathyroidism- Dx

A
  • Elevated Ca, PTH
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10
Q

Hyperparathyroidism- Tx

A
  • Bisphosphanates
  • Propanalol
  • Surgery
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11
Q

Hypercalcemia- Eti

A
  • Hyperparathyroid -90% cases
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12
Q

Hypercalcemia- Sx

A
  • constipation & polyuria
  • Leathargy, stupor & coma
  • N/V, nephrolithiasis
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13
Q

Hypercalcemia- Dx

A
  • Elevated calcium, chloride & low bicarb suggests PTH

- Measure PTH to determine cause

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14
Q

Hypercalcemia- Tx

A
  • Bisphosphenates

- Establish euvolemia

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15
Q

Hypocalcemia- Eti

A
  • Hypoalbinemia

- Hypoparathyroidism (pseudo), vit D deficiency

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16
Q

Hypocalcemia- Sx

A
  • Chovestek & Trousseau
  • Muscle cramp & tetany
  • Laryngeospasm
  • Cataracts, calcification of basal ganglia
  • Convulsions, paresthesias & abd pain
17
Q

Hypocalcemia- Dx

A
  • Prolonged QT interval

- Low calcium, elevated phosphate

18
Q

Hypocalcemia- Tx

A
  • Calcium infusion or oral