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Maddy - NMSP Exam I - psych pharm > Pharm - Stimulants > Flashcards

Pharm - Stimulants Flashcards

1
Q

MOA stimulants used to treat ADHD

A

enhance neurotransmitter transmission by serving as a direct and indirect non-catecholamine sympathomimetics

  • block pre-synaptic re-uptake
  • interferes with VMAT
  • increase NE, DA, and 5-HT release
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2
Q

what is the main activity of methylphenidate when treating ADHD

A

blocking reuptake of dopamine and inhibiting neurotransmitter pre-synaptic reuptake

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3
Q

“common” side effects of stimulants

A
  • dyspepsia/GI distress/N/V
  • HA
  • decreased appetite
  • insomnia
  • anxiety/jitteriness
  • irritability/aggression/agitation
  • elevated BP/HR
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4
Q

“rare” side effects of stimulants

A
  • priapism (painful, persistent erection of penis)
  • seizures
  • sudden cardiac death
  • stroke and MI
  • chemical leukoderma
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5
Q

in what pts should you use caution when prescribing stimulants

A

those with:

  • marked anxiety/agitation
  • symptomatic CV dz
  • moderate-severe HTN
  • glaucoma
  • motor tics/tourettes
  • bipolar/psychoses
  • seizures
  • hx drug abuse
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6
Q

what is the onset of activity and supply info for stimulants

A

onset is 14 hours

controlled substances –> 1 month supply, no refills, no samples

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7
Q

what form does adderall (dextroamphetamine/AMP) come in

A

tablet

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8
Q

what form does ProCentra (dextroamphetamine sulfate) come in

A

liquid

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9
Q

what form does Evekeo (amphetamine sulfate) come in

A

capsule

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10
Q

what form does Zenzidi (dextroamphetamine) come in

A

tablet

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11
Q

list the immediate release amphetamine based stimulants used to treat ADHD

A
  • adderall
  • procentra
  • evekeo
  • zenzidi
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12
Q

list the extended release amphetamine based stimulants used to treat ADHDA

A
  • adderall XR
  • dexedrine
  • dyanavel XR
  • Vyvanse
  • mydayis
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13
Q

what form does adderall XR come in

A

capsule

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14
Q

what form does dexedrine come in

A

capsule

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15
Q

what form does dyanavel XR come in

A

liquid

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16
Q

what form does Vyvanse come in

A

capsule

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17
Q

what form does Mydayis come in

A

capsule

18
Q

what is the one liquid extended release amphetamine based stimulant

A

dyanavel XR

19
Q

dosing and age group for adzenys XR-ODT

A

QD dosing

ages 6+

20
Q

list the immediate release methylphenidate-based stimulants used to treat ADHD

A
  • focalin
  • methylin
  • ritalin
21
Q

what form does focalin come in

A

tablet

22
Q

what form does methylin come in

A

liquid

23
Q

what form does ritalin come in

A

tablet

24
Q

list the sustained release methylphenidate-based stimulants used to treat ADHDA

A
  • ritalin SR

- desoxyn

25
Q

what form does ritalin SR come in

A

tablet

26
Q

what form does desoxyn come in

A

tablet

27
Q

list the extended release methylphenidate-based stimulants used to treat ADHD

A
  • aptensio XR
  • concerta
  • comtempla XR-ODT
  • daytrana
  • focalin XR
  • metadate CD
  • ritalin LA
  • quillichew
  • quillivant XR
28
Q

what extended release methylphenidate-based stimulants used to treat ADHD come in capsule form

A
  • aptensio XR
  • focalin XR
  • metadate CD
  • ritalin LA
29
Q

what extended release methylphenidate-based stimulants used to treat ADHD come in tablet form

A
  • concerta

- contempla XR-ODT

30
Q

what extended release methylphenidate-based stimulants used to treat ADHD come in transdermal patch form

A

daytrana

31
Q

what extended release methylphenidate-based stimulants used to treat ADHD come in chewable tablet form

A

quillichew

32
Q

what extended release methylphenidate-based stimulants used to treat ADHD come in liquid form

A

quillivant XR

33
Q

MOA non-stimulants for ADHD treatment

A

enhance neurotransmitter transmission via:

  • inhibit NE pre-synaptic reuptake
  • agonist of CNS alpha 2A adrenergic receptors
34
Q

onset of activity, what patients, and schedule for non-stimulants

A

onset: 1-4 weeks
patients: those intolerant of stimulant effects or those resistant to using stimulants
- schedule: non-scheduled, refills and samples allowed up to 1 year

35
Q

list the non-stimulant

A

atomoxetine/strattera ER

36
Q

what form does atomoxetine/strattera ER come in

A

capsule

37
Q

adverse effects atomoxetine/strattera ER

A
  • nervousness
  • sleep problems
  • suicidal thoughts
38
Q

what is atomoxetine/strattera ER metabolized by

A

CYP2D6

39
Q

list the anti-hypertensives

A
  • clonidine/kapvay ER

- guanfacine/intuniv ER

40
Q

what forms do the anti-hypertensives come in

A

tablets

41
Q

what is the dosing and patient age for the anti-hypertensives (guanfacine and clonidine)

what titration is necessary with these medications

A

every day dosing

pts 6+

downward dose titration over 1+ weeks do reduce risk of rebound hypertension

Maddy - NMSP Exam I - psych pharm (23 decks)

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