Pharm - Drugs of Abuse Flashcards
compare tolerance, sensitization, and withdrawal
tolerance: decreased response to a drug, necessitating larger doses to achieve the same effects
sensitization: increased response with repetition of same dose of drug
withdrawal: adaptive changes that become fully apparent once drug exposure is terminated
list the criteria and examples for a schedule 1 drug
criteria: no medical use, high addiction potential
examples: heroin, LSD, MDMA, PCP, flunitrazepam
list the criteria and examples for a schedule 2 drug
criteria: medical use, high addiction potential
examples: amphetamines, cocaine, short acting barbiturates, strong opioids
list the criteria and examples for a schedule 3 drug
criteria: medical use, moderate abuse potential
examples: ketamine, moderate opioids, anabolic steroids, barbiturates, dronabinol
list the criteria and examples for a schedule 4 drug
criteria: medical use, low abuse potential
examples: benzos, most hypnotics, weak opioids, chloral hydrate
compare duration of symptoms between:
- alcohol
- tabacco
- marijuana
- inhalants
- stimulants
- depressants
- hallucinogens
- narcotics
- PCP
- alcohol: 1hr/serving
- tabacco: 20 mins
- marijuana: 2-4 hours
- inhalants: 5 mins-8 hrs
- stimulants: 5 mins-12 hrs
- depressants: 1-16 hrs
- hallucinogens: 5 mins-12 hrs
- narcotics: 4-24 hrs
- PCP: 4-6 hrs
compare “other” symptoms between:
- alcohol
- tabacco
- marijuana
- inhalants
- stimulants
- depressants
- hallucinogens
- narcotics
- PCP
- alcohol: odor on breath, slurred speech
- tabacco: odor on breath, stained fingers/clothes
- marijuana: red eyes, eyelid tremors, appetite
- inhalants: odor, nausea, HA, disoriented
- stimulants: jittery, talkative, runny nose
- depressants: drowsy, slurred speech
- hallucinogens: paranoia, memory loss
- narcotics: euphoria, sleepy
- PCP: confused, aggressive, sweaty
what are the overdose effects of amphetamines, methylphenidate, and cocaine
- agitation
- HTN
- tachy
- delusions
- hallucinations
- hyperthermia
- seizures
- death
what are the withdrawal effects of amphetamines, methylphenidate, and cocaine
- apathy
- irritability
- increased sleep time
- disorientation
- depression
what are the overdose effects of barbiturates, benzos, and ethanol
- slurred speech
- drunken behavior
- dilated pupils
- weak and rapid pulse
- clammy skin
- shallow breathing
- coma, death
what are the withdrawal effects of barbiturates, benzos, and ethanol
- anxiety
- insomnia
- delirium
- tremors
- seizures
- death
what are the OD effects of heroine and other strong opioids
- constricted pupils
- clammy skin
- nausea
- drowsiness
- respiratory depression
- coma, death
what are the withdrawal effects of heroine and other strong opioids
- nausea
- chills
- cramps
- lacrimation (flow of tears)
- rhinorrhea
- yawning
- hyperpnea (increased depth and rate of breathing)
- tremor
what is used to treat nicotine addiction
- varenicline (chantix)
- nicorette
- nicoderm CQ
what opioid receptor antagonists are used to treat opioid dependence and addiction
- naloxone (narcan)
- naltrexone
