Clin - Psychotic Disorders Flashcards

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1
Q

when is the typical onset of schizophrenia

A

late adolescence and early adulthood

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2
Q

what are some precipitating events to schizophrenia

A
  • psychosocial stressors
  • traumatic events
  • drug and alcohol abuse
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3
Q

what are some prodromal signs and symptoms for schizophrenia

A

few close friends as adolescent

minimal social activities

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4
Q

describe the genetic influence of schizophrenia

A

monozygotic twins: 40-50%

dizygotic twins: 10-15%

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5
Q

what is the association between schizophrenia and early life complications (ELCs)

A

ELCs increase risk for schizophrenia by 1.5-2x

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6
Q

in addition to mesolimbic brain areas, where else is dopamine dysregulation seen in schizophrenic patients

A

amygdala and prefrontal cortex

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7
Q

how are cortisol levels associated with schizophrenia

A

people with schizophrenia experience both heightened and decreased cortisol secretion

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8
Q

what are the positive symptoms of schizophrenia

A
  • delusions
  • hallucinations
  • disorganized thinking (speech)
  • grossly disorganized or abnormal motor behavior
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9
Q

compare hypnagogic and hypnopompic hallucinations

A

hypnagogic: occurring while falling asleep
hypnopompic: occurring while waking up

**NOT indicative of psychosis

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10
Q

what are types of disorganized thinking (speech)

A
  • tangential
  • derailment or loose associations
  • incoherence or “word salad’
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11
Q

what is catatonic excitement

A

purposeless and excessive motor activity without obvious cause

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12
Q

what is negativism

A

resistance to instructions

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13
Q

what type of inappropriate or bizarre posture do schizophrenic patients show

A

waxy flexibility

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14
Q

what grossly disorganized motor behavior is seen in schizophrenic patients

A
  • catatonic behavior
  • catatonic excitement
  • negativism
  • inappropriate or bizarre posture (waxy flexibility)
  • mutism and stupor
  • repeated stereotyped movements
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15
Q

compare the diagnosis of schizophrenia between adults and children/adolescents

A

adults: most of the time after onset of sx the level of functioning is far below what it was prior to onset

children/adolescents: failure to achieve expected level of functioning

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16
Q

if the patient has a history of autism spectrum disorder or a communication disorder of childhood onset, how does this affect diagnosing schizophrenia

A

the diagnosis of schizophrenia is made only if there are prominent delusions or hallucinations for at least one month in addition to the other required sx of schizophrenia

17
Q

which second-gen antipsychotic used for tx of schizophrenia is more commonly associated with agranulocytosis?

A

clozapine

18
Q

other than medication what types of treatment can help schizophrenic patients

A

community treatment

  • integrated behavioral medicine clinics
  • residential living facilities
  • care managers

self help programs

ECT

benzos for catatonic disorder

19
Q

compare:

  • schizoid
  • schizotypal
  • schizophrenia
  • schizoaffective
A

schizoid: very introverted and voluntarily withdraws from social interactions
- schizotypal: schizoid sx + magical thinking and odd behavior
- schizophrenia: schizotypical + psychosis
- schizoaffective: schizophrenia + mood disorder