Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Nplex II > Pharm randoms > Flashcards

Pharm randoms Flashcards

1
Q

Is gentamicin compatible with breastfeeding?

A

Yes. Low transfer and low oral availability

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

If a woman has a UTI and is pregnant, what abx?

A

amoxicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Are macrolides safe in pregnancy?

A

Erythromycin and Azithromycin are considered safe, but may alter bowel flora

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Are fluoroquinolone safe in lactation?

A

Avoid them!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Cephalosporins safe in lactation?

A

Safe with low milk transfer. 3rd gens like ceftriaxone May alter bowel flora

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Penicillins are safe in lactation?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Are tetracyclines safe in breastfeeding?

A

Definitely not. May cause dental staining and weird bone development

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Is fluconazole safe while breastfeeding?

A

Might accumulate and cause harm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Is Nitrofurantoin safe in breastfeeding?

A

Avoid in G6PD infants due to risk of hemolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Is TMP-SMX safe in breastfeeding?

A

Avoid in infants with hyperbilirubinaemia and G6PD deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What abx are safe in pregnancy

A

Most are except for nitrofuran derivatives and sulfonamides.. but these are sometimes used in 2nd and 3rd trimesters to tx and prevent uti

Tetracyclines are contraindicated

Macrolides aren’t always safe
(erythromycin CI in pregnancy,
clarithromycin is Cat-C in PG, azithromycin is Cat-B)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What abx target cell wall

A

penicillins and cephalosporins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

your patient has a penicillin allergy and you want good gram +/- coverage… what do?

A

Well… don’t use a cephalosporin if they have a hx of anaphylaxis. If they just had a rash, it’s probably safe if necessary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What abx interfere with bacterial enzymes

A

quinolones, sulfonamides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which abx are bacteriostatic

A

ahminoglycosides, macrolides, tetracyclines.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What abx offer best gram+ coverage

A

penicillin G, vancomycin, bacitracin
1st gen cephalosporins (Cephalexin)

17
Q

what abx offer best gram - coverage

A

Aminoglycosides (gentamicin, neomycin)
polymyxins
4th gen cephalosporins

18
Q

what abx offer best gram- coverage

A

Aminoglycosies (gentamicin

19
Q

What are broad spectrum antibiotics?

A

Quinolones, ampicillin
3rd gen cephalosporins
tetracyclines
sulfonamides

20
Q

Acute cystitis abx for a non-pregnant woman

A

Nitrofurantoin

21
Q

Acute cystitis abx for someone without renal failure

A

nitrofurantoin or tmp-smx double strength

22
Q

Pyelnephritis outpatient abx

A

ciprofloxacin

23
Q

adverse effects of ciprofloxacin

CI of copra

A

achilles tendon rupture/tendon pathology

DO NOT USE IN KIDS UNDER 18 (same for all other fluoroquinolones)

24
Q

AE’s of aminoglycosides

A

OTOTOXICITY

25
Q

Rifampin is used for what?

A

TB.
MRSA
Prophylaxis of meningitis
Gonorrhea

26
Q

What should rifampin be administered with

A

B6

27
Q

What drug do we use for traveler’s diarrhea

A

Rifaximin

Nplex II (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions