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Nplex II > Bot Med drug interactions > Flashcards

Bot Med drug interactions Flashcards

1
Q

Achillea Millefolium

A

Antagonizes PPI.

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2
Q

Aconitum

A

None

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3
Q

Actaea racemosa

A

HRT therapy leads to estrogen excess.

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4
Q

Aesculus Hippocastanum

A

None

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5
Q

Allium Cepa/Sativum

A

Potentiates Hypoglycemics, Anticoagulants

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6
Q

Aloe Vera

A

Will make you shit your pants so don’t take with hypokalemics

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7
Q

Althaea

A

None except maybe reduced absorption

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8
Q

Angelica Sinensis

A

Potentiates anticoagulants

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9
Q

Arctium Lappa

A

Antagonizes PPIs, potentiates hypoglycemics.

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10
Q

Arctostaphylos Uva-ursi

A

Vitamin C and cranberry will acidify urine, which is not what we want when using this herb

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11
Q

Arnica Montana

A

None

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12
Q

Artemisia annua

A

Combo with iron for ULTIMATE POWER

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13
Q

Artemisia absinthe

A

Antagonizes PPIs, potentiates hypoglycemics.

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14
Q

Artemisia Vulgaris

A

Antagonizes PPIs, potentiates hypoglycemics.

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15
Q

Asclepius Tuberosa

A

Interact w cardiac glycosides

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16
Q

Aspidosperma Quebracho

A

None

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17
Q

Astragalus Membranaceus

A

Potentiates acyclovir and interferon therapy. May antagonize corticosteroids

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18
Q

Atropa Belladonna

A

Potentiates anticholinergics and TCAs

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19
Q

Avena Sativa

A

None

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20
Q

Bacopa Monnieri

A

Bacopa might increase levothyroxine levels by Inhibiting CYP450. Might potentiate CCBs and sedatives.

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21
Q

Baptisia Tincotra

A

None

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22
Q

Berberis aquifolium

A

Antagonizes PPI because its a bitter

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23
Q

Berberis Vulgaris

A

Bitters antagonize PPIs. Potentiates phenobarbital. Gut motility stuff

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24
Q

Boswellia Serrata

A

Enhances NSAIDs

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25
Q

Bryonia Alba

A

none

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26
Q

Calendula officinalis

A

none

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27
Q

Camellia sinensis

A

Ciprofloxacin inhibits caffeine elimination, may cause HTN with MAOIS, OCPs make you hyper on this

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28
Q

Cannabis Sativa

A

Potentiates opiats

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29
Q

Capsella Bursa-Pastoris

A

Anticoagulant

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30
Q

Capsicum Frutescens

A

Anticoagulant

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31
Q

Cassia Senna

A

Will make you shit your brains out so we don’t want to take with more hypokalemic

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32
Q

Caulophyllum Thalictroides

A

May interfere with angina tx (nitroglycerin)

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33
Q

Ceanothus Americanus

A

ANTAGONIZES warfarin

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34
Q

Centella Asiatica

A

None

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35
Q

Chamaelirium Luteum

A

Potentiates warfarin

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36
Q

Chelidonium Majus

A

None

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37
Q

Chionanthus virginicus

A

None

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38
Q

Cineraria Maritima

A

Hepatotoxic drugs do not go with this

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39
Q

Coleus Forskohli

A

May potentiate cardiac glycosides, anticoagulants, insulin, hypoglycemics, antihistamines

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40
Q

Commiphora Mukul

A

Decreases availability of beta blockers and CCBs by inducing CYP 450

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41
Q

Commiphora molmol`

A

Potentiates insulin and hypoglycemic

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42
Q

Convallaria Majalis

A

CALCIUM promotes arrhythmias, avoid use with hypokalemic, corticosteroids.

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43
Q

Cordyceps

A

Potentiates epinephrine

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44
Q

Corydalis

A

Similar action to CCBs

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45
Q

Crataegus

A

HYPERTENSION WITH BETA BLOCKERS. Tannins so reduces absorption.

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46
Q

Curcuma Longa

A

Potentiates anticoagulants

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47
Q

Cynara Scolymus

A

Antagonizes PPIs (because its a bitter), potentiates atorvastatin (bc its so good at tx hyperlipidemia)

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48
Q

Datura stramonium

A

Potentiates anticholinergics

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49
Q

digitalis

A

Avoid with hypokalemic drugs, corticosteroids, anti-arrhythmias, with CALCIUM.

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50
Q

Echinacea augustifolia

A

Antagonizes immune suppression therapies

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51
Q

Eleutherococcus Senticosus

A

Not with immunosuppressive therapy.

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52
Q

Ephedra Sinica

A

Potentiates sympathomimetics. Antagonizes alpha and beta blockers

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53
Q

Equisetum Arvense

A

May antagonize anticoagulants

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54
Q

Eschscholzia California

A

Potentiates MAOIs and SSRIs

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55
Q

Eucalyptus Globulus

A

None

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56
Q

Eupatorium Perfoliatum

A

Synergy with hepatotoxic drugs

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57
Q

Eupatorium Purpureum

A

Synergy with hepatotoxic drugs

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58
Q

Euphrasia Officinalis

A

None

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59
Q

Foeniculum Vulgare

A

None

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60
Q

Galium Aparine

A

None

61
Q

Fucus Vesiculosis

A

Decreased absorption of lots of things (calcium, potassium, iron, sodium). Interacts with levothyroxine. Potentiates amiodarone and lithium.

62
Q

Ganoderma Lucidum

A

Antagonizes amphetamines bc its so sleepy. Immunostimulaating so not with immunosuppressives. Potentiates barbiturates and anticoagulants.

63
Q

Gelsemium sempervirens

A

Potentiates aspirin.

64
Q

Gentian Lutea

A

Antagonizes ppi’s.

65
Q

Geranium Maculatum

A

Reduces absorptions

66
Q

Ginkgo Biloba

A

Potentiates anticoagulants

67
Q

Glycyrrhiza Glabra

A

Potentiates cardiac glycosides, corticosteroids, hypokalemics.

68
Q

Grindelia Robusta

A

None

69
Q

Hamamelis Virginiana

A

Decreases absorption

70
Q

Harpagophytum Procumbens

A

Antagonizes PPI because its a bitter

71
Q

Humulus Lupulus

A

Antagonizes PPI because its a bitter

72
Q

Hydrangea Arborescens

A

None

73
Q

Hydrastis Canadensis

A

PPI antagonism and potentiates barbiturates, reduces B vitamin absorption

74
Q

Hyoscyamus Niger

A

Potentiates anticholinergics and tricyclics.

75
Q

Hypericum Perforatum

A

Similar action to benzodiazepines, TCAs. Serotonin syndrome. May potential anti-retrovirals. Otherwise is an inducer of CYP450 3a4 so guess that it will lower concentrations of most drugs on nplex.

76
Q

Iris Versicolor

A

None

77
Q

Juniperus Communis

A

Antagonizes PPI.

78
Q

Larrea Tridentata

A

Inhibits CYP450 so may raise toxicities of drugs.

79
Q

Leonurus Cardiaca

A

None

80
Q

Leptandra Virginica

A

Antagonizes PPI, doxycycline, reduces B vitamin absorption. Antagonizes Podophyllum (that’s weird)

81
Q

Ligusticum Porteri

A

Potentiates anticoagulants

82
Q

Ligustrum Lucidum

A

May antagonize immunosuppressives.

83
Q

Linum Usitassitum

A

Interferes with aromatase inhibitors (anastrozole), 5-alpha reductase inhibitors (finasteride). May potentate warfarin

84
Q

Lobelia Inflata

A

None (yeah right)

85
Q

Lomatium Dissectum

A

none

86
Q

Lycopus Virginicus

A

Interacts with levothyroxine

87
Q

Matricaria Camomila

A

May potentiate sedatives

88
Q

Medicago Sativa

A

Potentiates hypoglycemics, antagonizes anticoagulants

89
Q

Melaleuca alternifolia

A

None

90
Q

Melissa Officinali

A

None

91
Q

Mentha X Piperita

A

None

92
Q

Mitchella Repens

A

None

93
Q

Momordica Charantia

A

May potentiate hypoglycemics

94
Q

Panax ginseng

A

Potentiates caffeine, MAOIS, morphine, insulin, immune drugs. Antagonizes warfarin but might cause bleeding

95
Q

Passiflora Incarnata

A

Potentiates SSRIS, MAOIs, Sedatives, barbiturates, benzos

96
Q

Pausinystalia Yohimbe

A

Potentiates alpha blockers (Carvedilol, risperidone, tamsulosin, trazodone), TCA, MAOIs, Sympathomimetics.

97
Q

Phytolacca Americana

A

None

98
Q

Piper methysticum

A

Antipsychotics, benzos

99
Q

Piscidia erythrina

A

Potentiates sedatives

100
Q

Plantar major

A

Mucilages decrease absorption

101
Q

Podophyllum

A

None

102
Q

Prunus Serotina

A

None

103
Q

Prunus Pygeum

A

Potentiates finasteride

104
Q

Pulsatilla vulgaris

A

None

105
Q

Quercus Rubra

A

Tannin effect

106
Q

Rauwolfia serpentina

A

Antagonizes hctz, MAOIs, TCA, digoxin, sympathomimetics (albuterol, epinephrine etc)

107
Q

Rhamnus

A

Avoid with hypokalemic drugs, corticosteroids, anti-arrhythmias, with CALCIUM.

108
Q

Rhodiola Rosea

A

Inhibits CYP450. Antagonizes immune suppression. Potentiates SSRIs, sedatives, barbiturates, benzo, opiates

109
Q

Rosmarinus officinalis

A

Potentiates doxorubicin and vinblastine

110
Q

Rubus Idaeus

A

May antagonize anticoagulants. Has tannins.

111
Q

Rumex crispus

A

Avoid with hypokalemic drugs, corticosteroids, anti-arrhythmics

112
Q

Salix alba

A

Potentiates acetaminophen and NSAID

113
Q

Salvia officinalis

A

N/a

114
Q

Sambucus nigra

A

none

115
Q

Sanguinaria Canadensis

A

Nausea w other meds

116
Q

Schizandra chinensis

A

Potentiates phenobarbital, diminishes acetaminophen toxicity, inhibits CYP450

117
Q

Scutelleria Baicalensis

A

Potentiates warfarin, sedatives, barbiturates, benzos

118
Q

Scutellaria lateriflora

A

none

119
Q

Selenicereus grandiflorus

A

Potentiates MAOIs

120
Q

Serenoa Repens

A

Potentiates anticoagulants and other 5-alpha-reductase inhibitors

121
Q

Silybum Marianum

A

Protects against cisplatin, cyclosporine, methotrexate toxicities, but POTENTIATES DOXORUBICIN

122
Q

Smilax spp

A

Increased absorption

123
Q

Solidago spp

A

None

124
Q

Symphytum officinale

A

Synergy with hepatotoxic drugs

125
Q

Tanacetum parthenium

A

Antagonizes morphine, potentates warfarin.

126
Q

Tanacetum Vulgare

A

None

127
Q

Taraxacum official

A

Potentiates lithium, hypoglycemic drugs, reduces vitamin B absorption

128
Q

Theobroma Cacao

A

Hypertensive crisis with use of MAOI

129
Q

Thuja occidnetalis

A

none

130
Q

Thymus vulgaris

A

Potentiates warfarin

131
Q

Tilea europa

A

Decreased iron absorption

132
Q

Tribulus terrestris

A

Potentiates cardiac glycosides, B blockers, and ccb’s

133
Q

Trifolium Pratense

A

Potentiates anticoagulants

134
Q

Tussilago farfara

A

Hepatotoxic drug synergy

135
Q

Ulmus Rubra

A

May reduce absorption due to mucilage

136
Q

Urtica dioica

A

none

137
Q

Usnea Barbata

A

none

138
Q

Vaccinium Myrtillus

A

May potentiate insulin

139
Q

Valeriana officinali

A

May potentiate sedatives

140
Q

Veratrum album

A

None

141
Q

Verbascum thapsus

A

none

142
Q

Verbena officinalis

A

Antagonizes warfarin

143
Q

Viburnum opulus

A

none

144
Q

Vinca Major

A

none

145
Q

Viscum album

A

Potentiates MAOIs

146
Q

Vitex agnus castus

A

none

147
Q

Withania Somnifera

A

Potentiates barbiturates, epileptics, immunosuppressives

148
Q

Zingiber officinalis

A

Potentiates anticoagulants, antagonizes antacids. Protects against aspirin gut damage

Nplex II (10 decks)

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