Pharm: Module 8 Sympathetic/Parasympathetic Flashcards

1
Q

describe sympathetic

A
adrenergic receptors
energize
fight or flight 
increased HR and RR
alpha and beta receptors
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2
Q

describe parasympathetic

A

cholinergic receptors
stabilize
nicotinic/muscarinic receptors

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3
Q

enhance

A

agonist

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4
Q

block (opposite effect)

A

antagonist

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5
Q

describe alpha 1 adrenergic agonist receptors

A

increase cardiac contractility and vasoconstriction
dilates pupils, decreases salivary gland secretion
increase bladder and prostate contraction

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6
Q

describe alpha 2 adrenergic agonist receptors

A

inhibits norepinephrine release
promotes vasodilation and decreases BP
decreases GI motility and tone

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7
Q

describe beta 1 adrenergic agonist receptors

A

increase cardiac contractility and HR

increaser renin secretion and BP

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8
Q

describe beta 2 adrenergic agonist receptors

A
decrease GI tone and motility
bronchodilation
increase blood flow to skeletal muscles
relaxes SM of uterus
activates liver glycogenolysis(increase of BG)
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9
Q

directly stimulate receptor

A

direct acting

ie/ epinephrine

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10
Q

is epinephrine selective or nonselective

A
nonselective
alpha 1 (increase in BP), beta 1 (increase HR), beta 2 (bronchodilation)
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11
Q

what are the cautions associated with epinephrine

A

cardiac dysrhythmias, hypertension, hyperthyroidism, diabetes, pregnancy

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12
Q

what is epinephrine used for

A

anaphylaxis, anaphylactic shock, bronchospasms, asystole, cardiac arrest, cardiogenic shock, asthma attack

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13
Q

side effects of epinephrine

A

palpitations, tachycardia, insomnia, hyperglycemia

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14
Q

drug interactions of epinephrine

A

beta blocker (decrease action), digoxin (dysrhythmias), and TCAS/MAOIS (intensify action)

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15
Q

nursing interventions for epinephrine

A

monitor BP, HR, urine output

avoid adrenergic nasal spray and cold meds

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16
Q

is albuterol selective or nonselective

A

selective

acts on Beta 2

17
Q

what does albuterol promote

A

bronchodilation

relaxes muscles in airways and increases air flow to lungs

18
Q

what is albuterol used for

A

bronchospasm, asthma, bronchitis, COPD

19
Q

what is cautioned with albuterol

A

hypertension, diabetes, pregnancy, renal dysfunction

20
Q

side effects of albuterol

A

similar to epinephrine(Beta 1 stimulation)

tremors, tachycardia, palpitations, dysrhythmias

21
Q

drug interactions with albuterol

A

potentiates alcohol and other sedative drugs
give at low first dose to avoid hypotension
discontinue gradually

22
Q

is psudoenephrine selective or nonselective

A

nonselective agonist

works on Alpha 1, Alpha 2, and Beta 1

23
Q

what is psudoenephrine used as

A

nasal decongestive (nasal spray)
localized
not given more than 3 days

24
Q

who is not recommended to take psudoenephrine as a pill

A

hypertensive and cardiac patients because the pill is systemic

25
Q

describe adrenergic antagonists

A

block effects of adrenergic neurotransmitter
block alpha and beta receptor sites
opposite effects of agonists

26
Q

describe alpha 1 adrenergic antagonist receptor

A

vasodilation, dizziness
orthostatic hypotension, reflex tachycardia
suppresses ejaculation
decrease in contraction of SM

27
Q

describe beta 1 adrenergic antagonist receptor

A

decrease in cardiac contractility and pulse

28
Q

describe beta 2 adrenergic antagonist receptor

A

bronchoconstriction, contracts uterus, inhibits glycogenolysis

29
Q

is prazosin selective or nonselective

A

selective for alpha 1 receptors

alpha blocker

30
Q

what is prazosin used to treat

A

HTN< benign prostatic hypertrophy

31
Q

side effects of prazosin

A

hypotension, tachycardia, inhibition of ejaculation

32
Q

what is important to know about prazosin

A

fall risk due to dropping BP