Pharm - Hepatitis Flashcards

1
Q

Peginterferon-

A
  • Weekly injections x 48 weeks (once or 3x per week)

- Monitor response with HCV RNA

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2
Q

Ribavirin

A
  • Daily pill x 48 weeks in combination with peg interferon
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3
Q

Triple therapy

A
  • Protease inhibitor (telaprevir or boceprovir) plus peg interferon and ribaviron
  • Goal: sustained viral response or undetectable RNA
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4
Q

Triple therapy- Adverse effects

A
  • Serious interactions with other meds- CYT 450
  • Dysguesia
  • Anemia & neutropenia
  • Rash, pruritis, nausea
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