Jaundice Flashcards
1
Q
Gilbert Syndrome- Patho
A
Genetic mutation causes inability to conjugate bilirubin
Hereditary
2
Q
Gilbert Syndrome- Clin sx
A
Jaundice when stressed- Illness or exercise plus constitutional symptoms
3
Q
Hemolysis- Patho
A
Increased destruction of erythrocytes leading to release of bilirubin from liver
4
Q
Hemolysis- Sx
A
Jaundice
5
Q
Biliary obstruction- Patho
A
Blockage of biliary tree due to stone or carcinoma
6
Q
Biliary obstruction- Sx
A
RUQ pain, wt loss, jaundice, dark & light stools
7
Q
Hepatocellular disease- Patho
A
Carcinoma, toxin or other cause disrupts hepatocytes.
8
Q
Hepatocellular disease- SX
A
Malaise, anorexia, fever RUQ pain
- Hepatomegaly
- Vascular spiders
- Palmar erythema
- Sparse body hair
9
Q
Direct hyperbilirubinemia
A
- Indicates liver cause
- Due to decreased excretion into bile duct or backward leakage
- Cellular dysfunction, obstruction
10
Q
Indirect hyperbilirubinemia
A
- Break down of RBC. Overproduction, impairment or uptake of bilirubin
- Increased in hemolytic states, Gilberts
