Biliary tract disorders Flashcards

1
Q

Cholelithiasis- Eti

A
  • Most commonly cholesterol stones
  • Fat, female, forty
  • Pima & American- high incidence
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2
Q

Cholelithiasis- Sx

A
  • Asymptomatic
  • Infrequent, steady severe pain in epigastrum, RUQ
  • Sx present at night, resolve in 2-6 hrs
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3
Q

Cholelithiasis- Dx

A
  • US, may not be visible
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4
Q

Cholelithiasis- Tx

A
  • Nothing- NSAIDs for pain

- Resection if needed

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5
Q

Acute cholecystitis- Eti

A
  • 90% due to gallstone impaction & subsequent inflammation

- Acalculous rare- in critically ill patient, infectious agent

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6
Q

Acute cholecystitis- Sx

A
  • Precipitated by large/ fatty meal
  • Sudden, severe in epigastrum & rt hypochondrium
  • Vomiting reliefs
  • RUQ tenderness
  • Palpable gallbladder
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7
Q

Acute cholecystitis- Dx

A
  • Hepatobiliary nuclear imaging to show obstruction
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8
Q

Acute cholecystitis- Tx

A
  • Cholecystectomy

- Subsides with conservative measures- abx, iv feeding, analgesics

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9
Q

Chronic cholecystitis- Eti

A

Repeated episodes of acute or chronic gallbladder irritation

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10
Q

Chronic cholecystitis- Tx

A

Cholecystectomy

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11
Q

Choledocholithiasis- Eti

A
  • 15% of pt with gallstones
  • Rise with age
  • Stones in bile duct
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12
Q

Choledocholithiasis- Sx

A
  • Hx of biliary pain with jaundice
  • N/V
  • Recurring RUQ pain persists for hrs
  • Hepatomegaly
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13
Q

Choledocholithiasis- Dx

A
  • ERCP
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14
Q

Choledocholithiasis- Tx

A
  • Dilation & removal of stones with ERCP
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15
Q

Biliary Tract Carcinoma- Eti

A
  • 10-25% of hepatobiliary malignancy
  • 50-70 asian males
  • Hx of gall infections, polyps
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16
Q

Biliary Tract Carcinoma- Sx

A
  • Progressive jaundice
  • RUQ pain radiates to back
  • Fistula formation
  • Rapid deterioration
  • Palpable gallbladder
  • Pruritis & skin excoriations
17
Q

Biliary Tract Carcinoma- Dx

A
  • MRI
  • Cholangiography with biopsy
  • Fine needle aspiration
18
Q

Biliary Tract Carcinoma- Tx

A
  • Resection or biliary-enteric bypass

- Palliation

19
Q

Cholangitis- Sx

A
  • Charcot triad: pain, fever, & jaundice
  • Chills
  • AMS & hypotension
  • Shock & leukocytosis
20
Q

Cholangitis- Dx

A

ERCP

21
Q

Cholangitis- Tx

A

Cipro

22
Q

Primary biliary cirrhosis- Eti

A
  • Middle aged women
  • Insidious onset
  • Hx of UTI, smoking, hormone, hair dye
23
Q

Primary biliary cirrhosis- Sx

A
  • Asymptomatic
  • Fatigue & pruritis
  • Hepatosplenomegaly
  • Xanthomatous lesions
  • Steatorrhea, portal HTN
  • Orthostatic hypotension, cognitive dysfunction
  • Low bone density
24
Q

Primary biliary cirrhosis- Dx

A

Liver biopsy

25
Q

Primary biliary cirrhosis- Tx

A
  • Ursodeoxycholic acid
26
Q

Primary sclerosing cholangitis- Eti

A
  • 20-50 males
  • Assoc with ulcerative colitis
  • 10% risk of cholangiocarcinoma
27
Q

Primary sclerosing cholangitis- Sx

A
  • Progressive obstructive jaundice
  • Fatigue, pruritis, anorexia, indigestion
  • Esophageal varicies
28
Q

Primary sclerosing cholangitis- Dx

A
  • MR choliangiography

- Onion-skinning of liver- biopsy

29
Q

Primary sclerosing cholangitis- Tx

A
  • Cipro
  • Ursodeoxycholic acid
  • Balloon dilation
  • Stenting