Pharm Final 1 Flashcards

1
Q

short acting benzos

A

Alprazolam
Lorazepam
Oxazepam

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2
Q

Heparin full anticoag dosing

A

80 units/kg bolus followed by 18 units/kg/hr infusion IV

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3
Q

—Macrolide (except azithromycin) affect on CYP

A

Inhibit

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4
Q

Onset: Frovatriptan

A

slow onset/long duration

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5
Q

Metronidazole affect on CYP

A

Inhibit

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6
Q

Eliquis (Apixaban) DVT Dosing

A

10 mg twice daily for 7 days, then 5 mg twice daily thereafter

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7
Q

Xarelto (Rivaroxaban) DVT dosing

A

15 mg twice daily for 21 days, followed by 20 mg daily thereafter

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8
Q

Bactrim affect on CYP

—

A

Inhibit

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9
Q

Onset: Sumatriptan

A

fast onset

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10
Q

long acting benzos

A

Chlordiazepoxide
Clorazepate
Diazepam

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11
Q

Heparin prophylaxis

A

5,000 units SQ BID or TID

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12
Q

INR goal for Mechanical mitral valve

A

2.5-3.5

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13
Q

1st line for absence sz

A

Ethosuximide

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14
Q

what anti-epileptic levels can be checked

A

Carbamazepine (Tegretol)
Phenytoin (Dilantin)
Valproate sodium (Depakote, Depakene)

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15
Q

Short acting insulin

A

Regular insulin (Insulin R)

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16
Q

Heparin ACS dosing

A

60 units/kg bolus followed by 16 units/kg/hr infusion IV

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17
Q

rapid acting insulin

A

Insulin Aspart/Novolog
Insulin glulisine/Apidra
Insulin Lispro/ Humalog

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18
Q

—Phenobarbital affect on CYP

A

Induce

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19
Q

CYP Inhibitor effect on INR

A

Will increase INR

20
Q

—Phenytoin affect on CYP

A

Induce

21
Q

Long acting insulin

A

Lantus/Glargine

Levemir/Detemir

22
Q

Enoxaparin prophylaxis dosing

A

40 mg SQ Q24

If Cr clearance <30 ml/min: 30 mg SQ Q24

23
Q

Onset: Rizatriptan

A

fast onset

24
Q

Intermediate acting insulin

A

NPH Insulin (humulin/novolin)

25
Q

—Integrase inhibitors (navir’s) affect on CYP

A

Inhibit

26
Q

—Rifampin affect on CYP

A

Induce

27
Q

—Cyclosporine affect on CYP

—

A

Inhibit

28
Q

—Carbamazepine affect on CYP

A

Induce

29
Q

—St. johns wort affect on CYP

A

Induce

30
Q

intermediate acting benzos

A

Clonazepam

31
Q

Fluconazole affect on CYP

A

Inhibit

32
Q

1st line for neonatal seizures

A

Phenobarbital

33
Q

1st line for myoclonic seizures

A

Clonazepam

34
Q

Dosing for NAS

A

1.3 mg/kg/day

35
Q

Enoxaparin full anticoagulant dosing

A

1 mg/kg SQ Q12 hr or 1.5 mg/kg SQ Q24

36
Q

Cimetidine affect on CYP

A

Inhibit

37
Q

—Oxcarbazepine affect on CYP

A

Induce

38
Q

tPA stroke dosing

A

0.9 mg/kg (max of 90 mg)

10% as bolus, remaining 90% as IV infusion over 60 minutes

39
Q

Onset: Zolmitriptan

A

fast onset

40
Q

Onset: Naratriptan

A

slow onset/long duration

41
Q

Onset: Eletriptan

A

fast onset

42
Q

Amiodarone affect on CYP

A

Inhibit

43
Q

INR goal for Afib, DVT tx

A

2-3

44
Q

—Azoles affect on CYP

A

Inhibit

45
Q

CYP inducer effect on INR

A

Will decrease INR