Pharm Final 1 Flashcards

1
Q

short acting benzos

A

Alprazolam
Lorazepam
Oxazepam

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2
Q

Heparin full anticoag dosing

A

80 units/kg bolus followed by 18 units/kg/hr infusion IV

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3
Q

—Macrolide (except azithromycin) affect on CYP

A

Inhibit

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4
Q

Onset: Frovatriptan

A

slow onset/long duration

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5
Q

Metronidazole affect on CYP

A

Inhibit

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6
Q

Eliquis (Apixaban) DVT Dosing

A

10 mg twice daily for 7 days, then 5 mg twice daily thereafter

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7
Q

Xarelto (Rivaroxaban) DVT dosing

A

15 mg twice daily for 21 days, followed by 20 mg daily thereafter

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8
Q

Bactrim affect on CYP

—

A

Inhibit

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9
Q

Onset: Sumatriptan

A

fast onset

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10
Q

long acting benzos

A

Chlordiazepoxide
Clorazepate
Diazepam

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11
Q

Heparin prophylaxis

A

5,000 units SQ BID or TID

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12
Q

INR goal for Mechanical mitral valve

A

2.5-3.5

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13
Q

1st line for absence sz

A

Ethosuximide

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14
Q

what anti-epileptic levels can be checked

A

Carbamazepine (Tegretol)
Phenytoin (Dilantin)
Valproate sodium (Depakote, Depakene)

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15
Q

Short acting insulin

A

Regular insulin (Insulin R)

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16
Q

Heparin ACS dosing

A

60 units/kg bolus followed by 16 units/kg/hr infusion IV

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17
Q

rapid acting insulin

A

Insulin Aspart/Novolog
Insulin glulisine/Apidra
Insulin Lispro/ Humalog

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18
Q

—Phenobarbital affect on CYP

A

Induce

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19
Q

CYP Inhibitor effect on INR

A

Will increase INR

20
Q

—Phenytoin affect on CYP

21
Q

Long acting insulin

A

Lantus/Glargine

Levemir/Detemir

22
Q

Enoxaparin prophylaxis dosing

A

40 mg SQ Q24

If Cr clearance <30 ml/min: 30 mg SQ Q24

23
Q

Onset: Rizatriptan

A

fast onset

24
Q

Intermediate acting insulin

A

NPH Insulin (humulin/novolin)

25
—Integrase inhibitors (navir’s) affect on CYP
Inhibit
26
—Rifampin affect on CYP
Induce
27
—Cyclosporine affect on CYP | —
Inhibit
28
—Carbamazepine affect on CYP
Induce
29
—St. johns wort affect on CYP
Induce
30
intermediate acting benzos
Clonazepam
31
Fluconazole affect on CYP
Inhibit
32
1st line for neonatal seizures
Phenobarbital
33
1st line for myoclonic seizures
Clonazepam
34
Dosing for NAS
1.3 mg/kg/day
35
Enoxaparin full anticoagulant dosing
1 mg/kg SQ Q12 hr or 1.5 mg/kg SQ Q24
36
Cimetidine affect on CYP
Inhibit
37
—Oxcarbazepine affect on CYP
Induce
38
tPA stroke dosing
0.9 mg/kg (max of 90 mg) | 10% as bolus, remaining 90% as IV infusion over 60 minutes
39
Onset: Zolmitriptan
fast onset
40
Onset: Naratriptan
slow onset/long duration
41
Onset: Eletriptan
fast onset
42
Amiodarone affect on CYP
Inhibit
43
INR goal for Afib, DVT tx
2-3
44
—Azoles affect on CYP
Inhibit
45
CYP inducer effect on INR
Will decrease INR