drug specifics test 1 Flashcards
H1 agonists (for sleep)
can cross BBB
interferon
works through all phases of viral process
What not to give in pt with cocaine intoxication
beta blockers
carbapenems can cause what at high enough dose
seizures
secondary amines
norepinephrine effect
sedating/anticholinergic reduced compared to tertiary
AUC/MIC
VANCO azithromycin FQs aminoglycosides tigencycline linezolid
MAOIs
lots of drug interactions
diet interaction
codeine transformed to
morphine
penciclovir and famcclovir
varicella and shingles
following activation, inhibit viral DNA synthesis
acyclovir and valacyclovir
inhibit viral DNA synthesis
clozapine
for recurrent suicidality, violence, comorbid substance abuse
REMS program: neutropenia
only second generation to show superiority to first
flumazenil (romazicon)
can cause seizures!
meperidine transformed to
normedperidine
build up can lead to seizures
ampho B
bind to fungal membrane component (ergosterol) to alter fungal cellular permeability
venlafaxine (effexor)
dose related hypertension; discontinuation syndrome
T>MIC
B-LACTAMS
vanco
macrolides
clindamycin
Fluoxetine (Prozac)
CNS activation
st. john’s wort interaction
CYP inducer
Fluvoxamine (luvox)
sedating
suvorexant (belsomra)
orexin antagonist
orexin involved in wakefullness
erection antagonist
citalopram (celexa)
QT prolongation
Escitalopram (lexapro)
most selective
tertiary amines
higher sedation
anticholinergic
serotonin effect
Paroxetine (Paxil)
sedating
