drug side effects test 1

Question 1

anti depressant
sedation
increased appetite/weight gain

Answer 1

mirtazapine/remeron

Question 2

anti depressant
Tremor
SEIZURES
lowest incidence of sexual dysfunction

Answer 2

Wellbutrin (bupropion)

Question 3

Non HIV antivirals
amphetamine like actions
confusion/psychosis/insomnia
problematic in children under 15 with renal/hepatic dz

Answer 3

Amantadine/ Rimantidine

Question 4

ABX
GI distress
superinfex
myopathy
peripheral neuropathy

Answer 4

daptomycin

Question 5

anti depressant
anticholinergic
CNS disturbance (seizure/tremors)

Answer 5

MAOI

Question 6

ABX

sudden cardiac death

Answer 6

macrocodes: biaxin

Question 7

HIV
lactic acidosis
severe hepatomegaly

Answer 7

NRTI

Question 8

Non HIV antivirals
dose dependent hemolytic anemia
mutagenic, teratogenic, embryotoxic
contraindicated in pts with sickle cell

Answer 8

ribavirin

Question 9

ABX
High incidence of nephrotoxicity esp with chronic dosing
ototoxicity

Answer 9

aminoglycosides

Question 10

HIV
rash (sometimes severe)
biotransformed by CYP450

Answer 10

NNRTI

Question 11

HIV
Endocrine system effects (hyperglycemia, hyperlipidemia, elevated transaminases)
Increased bleeding

Answer 11

Protease inhibitors

Question 12

ABX

high toxicity: ototoxicity, nephrotoxicity

Answer 12

polymyxins

Question 13

ABX
ototoxicity
tinnitus
Red-man syndrome
nephrotoxicity

Answer 13

vancomycin

Question 14

Non HIV antivirals
Bone marrow suppression
teratogenic, mutagenic, oncogenic potential

Answer 14

Ganciclovir/ valgancyclovir

Question 15

anti depressant
anticholinergic effects (dry mouth, constipation, urinary retention)

Answer 15

TCA

Question 16

FQ BBW

Answer 16

avoid use in myasthenia gravis

discontinue use at first sign of tendon issues/tendon rupture

Question 17

Anti fungal
serious adverse effects
nephrotoxicity, electrolyte loss
hematological problems

Answer 17

ampho B

Question 18

amphetamine toxicity

Answer 18

hyperthermia

Question 19

ABX
CNS effects
cartilage effects (ruptured tendons)
CARDIAC TOXICITY: QT prolongation

Answer 19

flouroquinolones

Question 20

ABX
teeth and bone accumulation
avoid use in pregnancy
photosensitvity

Answer 20

Tetracyclines

Question 21

Anti fungal
contraindicated in breast feeding
GI distress
endocrine (esp. ketaconazole)
QT prolongation
CYP inhibitor

Answer 21

Azoles

Question 22

anti cholinergic
alpha blockade (dizziness, increased BP)
weight gain
increased prolactin
movement disorders

Answer 22

antipsychotics

Question 23

anti depressant
Very sedating
priapism

Answer 23

trazodone/dyesrel

Question 24

ABX
GI upset
BBW: pseudomembranous colitis: C. diff!

Answer 24

clindamycin

Question 25

ABX N/V pulm rexns not good for use in really imapired

Answer 25

nitrofurantoin (macrobid)

Question 26

``` ABX crystal formation in urine hyperkalemia and elevated SCr blood problems hypersensitivity in 1st week of therapy kernicterus in newborns ```

Answer 26

sulfonamide

Question 27

BBW: abuse/addiction; cardiac events

Answer 27

simulants

Question 28

anti depressant GI disturbances Less sexual dysfunction constipation

Answer 28

SNRI

Question 29

``` anti depressant GI disturbances sexual dysfunction insomnia weight gain ```

Answer 29

SSRI

Question 30

ABX antabuse effect taste alterations neuropathy

Answer 30

Nitroimidazoles

Question 31

ABX N/V/D reversible bone marrow depression when used for more than 10 days Serotonin syndrome (MAOI)

Answer 31

oxazolidonones

Question 32

Non HIV antivirals HA, N/V REVERSIBLE RENAL DYSFUNCTION

Answer 32

Acyclovir/ valacyclovir