Pharm-Ch. 43 Flashcards
ACE Inhibitor
Angiotensin-Converting Enzyme Inhibitor. Drug that blocks ACE, the enzyme responsible for converting angiotensin I to angiotensin II in the lungs; this blocking prevents the vasoconstriction and aldosterone release related to angiotensin II.
Angiotensin II Receptors
specific receptors found in blood essels and in the adrenal gland that react with angiotensin II to cause vasoconstriction and release of aldosterone.
Baroreceptor
pressure receptor; located in the arch of the aorta and in the carotid artery; responds to changes in pressure and influences the medulla to stimulate the sympathetic system to increase or decrease blood pressure.
Cardiovascular Center
area of the medulla at which stimulation will activate the sympathetic nervous system to increase blood pressure, heart rate, and so forth.
Essential Hypertension
sustained blood pressure above normal limits with no discernible underlying cause.
Hypotension
sustained blood pressure that is lower than that required to adequately perfuse all of the body’s tissues.
Renin-Angiotensin-Aldosterone System
compensatory process that leads to increased blood pressure and blood volume to ensure perfusion of the kidneys; important in the continual regulation of blood pressure.
Shock
severe hypotension that can lead to accumulation of waste products and cell death.
Stroke Volume
the amount of blood pumped out of the ventricle with each beat; important in determining blood pressure.