Pharm Cardio Flashcards
1
Q
Use of and type of drug Bosentan
A
endothelin receptor antagonists (ERAs)
2
Q
What should Bosentan be switched to in pregnancy ?
A
sildenafil
As lead to malformations
3
Q
Benzbromaron MOA
A
a uricosuric agent& non-competitive inhibitor of xanthine oxidase second line Rx gout
4
Q
MOA Ambrisentan
A
As an endothelin A receptor antagonist
vasoconstriction and cell proliferation
5
Q
MOA Flecainide
A
blocks fast inward Na channels and slowly unbinds during diastole, prolonging the refractory period & shortens the duration of AP through the Purkinjie fibers.
