pharm- anxiety disorders Flashcards

1
Q

anxiety treatment based on severity
Mild anxiety –> ___
moderate –> ______
severe–> _____

A

mild –> cognitive behavioral therapy CBT
moderate –> CBT or meds or CBT + meds
Severe –> CBT + meds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

after how much time should you review ptt response to meds

A

4-6 weeks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

if after 4-6 weeks of anxiety treatment there is a partial response you should?

A

continue treatment, monitor progress and effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

if after 4-6 weeks of anxiety treatment there is no response or deterioration you should?

A

check adherence and review therapeutic engagement

rule out medication related effects as cause of current symptoms

review treatment foals and expectations

check treatment provided was consistent with guidelines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what SSRIs can be used for PDA, GAD, SAD

A

escitalopram
paroxetine
sertraline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

dosage of escitalopram

A

10-20mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

dosage of paroxetine

A

20-50 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

dosage of sertaline

A

50-150mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what SNRI can be used for PDA, GAD, SAD and what is the dosage

A

75-225mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what class of drug is pregabalin

A

calcium modulator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the MOA of pregabalin

A

binding presynaptically to the alpha2 and delta of voltage gated calcium channels (same as target)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the adverse effects of pregabalin

A

vertigo, dizziness, balance disorder, incoordination, ataxia, blurred vision

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what class of drug is buspirone

A

azapirone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is pregabalin used for

A

anxiety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is busipirone used for

A

anxiety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the MOA of buspirone

A

5HT receptor 1A partial agonist (binds to receptors on presynaptic neurons in the dorsal raphne and postsynaptic neurons in the hippocampus –> inhibting firing rate of 5HT containing neurons )

D(2) dopamine receptor antagonist (blocking presynaptic dopamine receptors)