Flores anxiety Flashcards

1
Q

Prevalence decreases with increased socioeconomic status

A

anxiety disorders

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2
Q

3 major neurotransmitters associated with anxiety disorders (which ones increase and which ones decrease)

A

(increase) noraderanaline,
(increase) serotonin
(decrease) GABA

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3
Q

what drugs increase noraderenaline and provoke frequent severe panic attacks?

A

beta adrenergic receptor agonists –> isoproterenol
alpha 2 adrenergic receptor antagonists –> yohibine

(Clonidine –> alpha 2 adrenergic receptor agonist so reduces anxiety)

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4
Q

acute stress causes an increase in serotonin in what areas of brain

A

prefrontal cortex, nucleus accumbens, amygdala, lateral hypothalamus

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5
Q

what drugs increase serotonin effects causing anxiety

A

McPP and fenfluaramine

also hallucinogens and stimulants like LSD and MDMA are associated with development of anxiety

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6
Q

what drug enhances the efficacy of GABA decreasing anxiety

A

benzos

at type A receptor

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7
Q

in the fear network : Viscerosensory info is conveyed to the ________ by the _____ and the ______

A

amygdala by the thalamus and primary viscerosensory cortices

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8
Q

In the fear network: contextual info is stored in the ________ and conveyed directly to the ______

A

hippocampus to the amygdala

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9
Q

Efferent pathways of amygdala relevant to anxiety , What brain regions causes:
physio and behavior arousal

A

locus cereleus by increasing NA

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10
Q

Efferent pathways of amygdala relevant to anxiety , What brain regions causes:
defensive behavior and postural freezing

A

periaqueductal gray regions

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11
Q

Efferent pathways of amygdala relevant to anxiety , What brain regions causes:
Activation of pHA (i think HPA), releasing adrenocorticoids

A

hypothalmic paraventricular nucleus

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12
Q

Efferent pathways of amygdala relevant to anxiety , What brain regions causes:
activation of sympathetic nerv system

A

lateral hypothalamic nucleus

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13
Q

Efferent pathways of amygdala relevant to anxiety , What brain regions causes:
influences in resp. rate and timing

A

parabrachial nucleus

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14
Q

the HPA axis physiological stress increases synthesis and release of ____

A

cortisol

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15
Q

what is the role of cortisol in stress

A

mobilizes and replenishes energy stores and contributes to increased arousal, vigilance, focused attn, and memory formation

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16
Q

the social learning model is part of the ________ theory and for what disorder?

A

behavioral

anxiety

17
Q

GAD must have sever anxiety and worry about several events or activities for most days/ for how long?

A

at least a 6 month period

18
Q

I GAD is associated with somatic symptoms how many needed? examples of symptoms

A

3 or more

muscle tension, irritability, difficulty sleeping, restlessness, easy fatigue, difficulty concentrating

19
Q

waxing and waning is what prevents this illness from recovery

20
Q

harboring panic disorder or major depressive disorder= =

21
Q

GAD treatment:
psychotherapy
Pharm.

A

cognitive and existential

first line –> SSRIs
Benzos (short term)
Buspirone ***
Second line –> sedating antihistamines, betaadrenergic blocks, clonidine

22
Q

Panic attack peaks within ____ min and lasts ______ needs ______ or more of specified symptoms

A

10 min
20-30 min/ >60 rare
4 or more

23
Q

panic attacks vs panic disorder

A

panic disorder are recurrent unexpected panic attacks worry more than a month

24
Q

________ patients have highest us of ERs of any psychiatric population

A

panic disorder

25
increase financial dependency because 70% quit or lose job/ many unable to drive further than 3 miles
panic disorder
26
Panic disorder treatment
first line: SSRIs benzos + antidepressants cognitive --> identify cognitive distortions and modify and or behavioral --> modify responses through exposure
27
1/3 of panic disorder patients also have
agoraphobia
28
patients with social phobia may release more __________ or ________ both centrally and peripherally than nonphobic or may be more sensitive to normal levels of them
norepinephrine and epinephrine
29
treatment for agoraphobia
first line SSRI benzos exposure therapy
30
treatment for specific phobia
exposure therapy
31
treatment for social phobia
first line: SSRI;s (paroxetine) SNRI (venlafaxine), benzos, beta blockers, buspirone exposure therapy