Pharm antibiotics Flashcards
1
Q
Importants of bacteria cell wall
A
- supports plasma membrane
- prevents bacteria from lysing
2
Q
what is bacteria cell wall made of
A
- Peptidoglycan which is crosslinked by transpeptidases
3
Q
difference between gram positive and gram negative
A
- gram pos = cell wall single layer
- gram neg = up to 40 layers
4
Q
cephalosporins function
A
- inhibites cell wall synthesis by disrupting transpeptidase enzyme
5
Q
qualities of cephalosporins and when it is useful
A
- more stable
- more expensive
- allergy
- toxicity
- resistance
6
Q
what is Bactericidal
A
Treatment of bacterium so organism is killed
(radiation and exposure to chemicals)
7
Q
What is Bacteriostatic
A
Treatment that restricts ability of bacterium to grown
(freezing or refrigerating)
8
Q
What is Narrow spectrum penicillin
A
- cover gram-positive infections
(benzo-penicillin)
9
Q
what is Braod spectrum penicillin
A
target gram- positive/negative infections
(Ampicillin)