Pharm, ADHD Flashcards

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1
Q

triad to ADHD

A

inattentiveness, hyperactivity, impulsiveness

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2
Q

onset ADHD

A

before age 12

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3
Q

DSM5 criteria ADHD

A

6+ Sx of inattention and or hyperactivity and impulsivity
and!!
-onset before 12 y.o
-impairment in 2 settings (school and home)
-impairment in social function
-no other pervasive disorder

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4
Q

combined ADHD

A

hyperactivity and inattention forms

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5
Q

treatment and management of ADHD

A

education for patient, parents, teachers, physician

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6
Q

medication effects for ADHD

A

dec fidgeting, interruption, aggressiveness, antisocial behavior,
inc: peer acceptance, efficiency, on task behavior, accuracy, short term memory, parent- child interactions, performance on motor tasks

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7
Q

what is methylphenidate

A

ritalin, methylin

stimulant

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8
Q

forms of ritalin

A

short acting, intm acting and long acting

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9
Q

what is dexmethylphenidate

A

focalin

stimulant

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10
Q

dextroamphetamine

A

dexedrine

stimulant

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11
Q

amphetamine mixed salts

A

adderall

sitmulant

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12
Q

disdexamfetamine

A

Vyvanse
stimulant
longer duration
cannot be crushed and injected to get high

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13
Q

Methylphenidate MOA

A

increase DA from blocking reuptake

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14
Q

atomextine

A

NE reuptake inhibitor

increase prefrontal DA

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15
Q

action of guanfacine and clonidine

A

decrease CNS sympathetic outflow

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16
Q

action of wellbutrin and TCAs

A

increase serotonin

17
Q

expected benefits with stimulants

A

improved concentration

all other benefits secondary

18
Q

problems with stimulants

A

misinformation
controlled substance
adverse effects

19
Q

adverse effects stimulants

A

sleep disturbance
appetite suppression
tics
anemias

20
Q

active ingredient in majoirty stimulant meds

A

methylphenidate

21
Q

how long do intm formulations last

A

3-5 hours

22
Q

how long do long acting formulations work

A

10-12 hours

23
Q

DDI with stimulants

A

ascorbic acid or fruit juice dec absorption

sodium bicarb inc absorption

24
Q

effects of ADHD Tx and substance abuse

A

decreases risk for substance abuse

25
Q

clonidine uses

A

tics and HTN
manage sleep problems in children
aggression and self injurious behavior

26
Q

how does guanfacine work

A

stimulates a2 R

can cause bradycardia hypotension and syncope

27
Q

TCAs used in combo with stimulants to

A

Tx partially Txed ADHD

reduce stimulant induced insomnia and appetite suppression