Alcohol Disorders & Nicotine Flashcards
main component in alcohol
ethyl alcohol
fermentation stops at what percent alcohol
12-13%
50% of all alcohol consumed by
10% of all drinkers
how many gr of ETOH per drink
10-14 grams
1.5 oz whiskey
12 oz beer
4 oz wine
how is blood alcohol concentration BAC measured
g/dL or mg/dL
1-2 drinks is 0.25g/dL or 0.25%
enzymes for alcohol metabolism
alcohol dehydrogenase
aldehyde dehydrogenase
where is alcohol dehydrogenase ADH found
liver
what does AldDH do
acetaldehyde to acetic acid
acetic acid in normal metabolic pathway becomes
carbon dioxide and water
peak BAC occurs how
30 minutes when alcohol taken orally
longer if taken with food
primary site alcohol absorption
small intestine
why is BAC higher in females than males
smaller total body water distribution due to fat stores
effects of BAC 50-100 mg/dL
sedation
subjective sensation of high
reaction slowed
80mg/dL legally drunk
how many drinks to cause 50-100 BAC in nontolerant
2-4 drinks in short period of time
BAC 100-200 mg/dL signs
impaired speech impaired motor function gait disturbance, clumsiness, ataxia increasingly disinhibited blackouts, anterograde amnesia disruption in REM sleep snoring and sleep apnea
BAC 200-300 mg/dL signs
emesis and stupor
BAC 300-400 mg/dL signs
coma
BAC 500+ mg/dL
respiratory depression and death