Drugs of Abuse, MacIntyre Flashcards

1
Q

mild abuse

A

2-3 Sx

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2
Q

moderate abuse

A

4-5 Sx

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3
Q

severe abuse

A

6+ Sx

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4
Q

other names for methamphetamine

A

meth, ice, crystal, Tina, T, speed, crank

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5
Q

how is meth taken

A

swallowed, snorted, injected, smoked

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6
Q

side effects meth

A

inc BP, HR, temp
dilated pupils, irregular heart beat, muscle twitching, mood disturbances, weight loss, psychosis, dental problems, teeth grinding, insomnia, violence, extreme agitation

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7
Q

meth toxic to what part in brain

A

dopamine nerve terminals

esp in frontal Cx

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8
Q

abuse and overdose of Rx stimulants can cause what Sx

A

anxiety, inc BP, HR, irritability, psychosis, weight loss, insomnia, CV effects, teeth grinding

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9
Q

abuse of Rx stimulants

A

on rise since 2007 when ADHD Dx

18-25 y.o

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10
Q

routes to administer bath salts

A

PO, inhale IV, vape

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11
Q

what happens with bath salts

A

surge in serotonin, norepi, dopamine

inc risk serotonin syndrome

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12
Q

bath salts cause what Sx

A

chest pains, inc BP, pulse, agitation, hallucinations, suicidality, extreme paranoia, delusions and extreme violence

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13
Q

most commonly used drug

A

marijuana

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14
Q

other names for weed

A

pot, green, 420, reefer, joint, blunt, dope, bud, mary jane

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15
Q

Sx of marijuana

A

euphoria, inc appetite, sense of relaxation

tachycardia, injected conjunctiva, dry mouth, paranoia, distored perceptions, difficulty with memory or complex tasks

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16
Q

what are the synthetic cannabinoids

A

spice, K2, fake week

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17
Q

how is synthetic weed taken

A

smoked or used as herbal infusion in drink

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18
Q

Sx synthetic week

A

anxiety and or psychosis

inc HR, BP vomiting, pulmonary irritation

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19
Q

names for cocaine

A

blow
snow
coke
“crack” when in powder

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20
Q

what is speedball

A

cocaine and heroin mixture

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21
Q

Sx of cocaine use

A

psychomotor agitaiton, dilated pupils
inc BP HR energy speech, euphoria, sinus problems, chest pain, risk of HIV or hepatitis transmission: MI through vasoconstriction

22
Q

molecular level effects of cocaine

A

surge of dopamine release then depletion causing depression accompanied by hyperinsomnia

23
Q

Psilocybin

A

magic mushrooms, shrooms, shroomies

24
Q

how are shrooms taken

A

swallowed or used in tea

25
effects of shrooms
distoreted perceptions, dilate pupils, hallucinations, cholinergic excess, inc BP HR Temp, anxiety, nausea
26
LSD
tablets capsules, liquid or absorbent paper | 8-12 hrs
27
effects of LSD
vivid hallucinations and distorts reality | can cause inc BP HR temp and insomnia
28
other names for ecstasy
MDMA, X, XTC, love drug, Molly, Adam, rave drug
29
how is X taken
orally | inc serotonin release, inc risk serotonin syndrome
30
effects of X
intense mental stimulation, emotional warmth, energy, disrupt temp homeostasis, nausea, chills, muscle cramps, teeth clenching, inc HR BP, pupillary dilation
31
neurotoxic effect X
destruction serotonergic neurons | lead to long term depression
32
what inhalants are abused
whippets, snappers products of glue etc huffing bagging or direct inhalation
33
effects of inhalants
rapid high, resemble EtOH intoxication | inhaling greater quantities can result in feelings of sensation loss and or consciousness
34
risks with inhalants
kidney failure, suffocation, hearing loss, limb spasms, bone marrow damage, organ damage or death can cause severe CNS damage, demyelination, atrophy and degeneration
35
other names for PCP
angel dust, wet, embalming fluid, sherms, ozone, wack | "Sernyl"
36
how is PCP taken
smoked, swallowed snorted
37
effects PCP
mimics schizophrenia like psychosis (NMDA antagonist) dissociation and detachment, inc BP/HR, nystagmus, sensation of heat, unusual strength, anesthetic efx, volatility and unpredictability,
38
names for ketamine
special K, vit K, jet, cat tranquilizer
39
how is ketamine taken
snorted ingested, IM
40
Sx of ketamine
inc dreams, ataxia, dec sensations, emotional warmth, epiphanies, hallucinations, near death experiences, blackouts
41
other names for benzos
bennies, xannies, anxiety pills
42
abuse of benzos causes
sedation, lethargy, memory problems ,ataxia, slurred speech
43
chronic benzo use leads to
upregulation NMDA R downregulation GABA R CNS hyperactivity in withdrawal risk of seixure
44
what drug can precipitate severe withdrawal of benzos
flumazenil
45
other names for barbituates
barbs, barbies, downers, nembies, seccies
46
what happens in barbituate withdrawal
seizure and withdrawal Sx
47
robo tripping
dextromethorphan DXM | dangerous with serotonin agents or anticholinergics
48
what are morning glory seeds
mescaline
49
what drugs dec seizure threshold
antipsychotics
50
do you give benzo to alcoholic
no