Drugs of Abuse, MacIntyre Flashcards

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1
Q

mild abuse

A

2-3 Sx

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2
Q

moderate abuse

A

4-5 Sx

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3
Q

severe abuse

A

6+ Sx

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4
Q

other names for methamphetamine

A

meth, ice, crystal, Tina, T, speed, crank

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5
Q

how is meth taken

A

swallowed, snorted, injected, smoked

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6
Q

side effects meth

A

inc BP, HR, temp
dilated pupils, irregular heart beat, muscle twitching, mood disturbances, weight loss, psychosis, dental problems, teeth grinding, insomnia, violence, extreme agitation

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7
Q

meth toxic to what part in brain

A

dopamine nerve terminals

esp in frontal Cx

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8
Q

abuse and overdose of Rx stimulants can cause what Sx

A

anxiety, inc BP, HR, irritability, psychosis, weight loss, insomnia, CV effects, teeth grinding

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9
Q

abuse of Rx stimulants

A

on rise since 2007 when ADHD Dx

18-25 y.o

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10
Q

routes to administer bath salts

A

PO, inhale IV, vape

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11
Q

what happens with bath salts

A

surge in serotonin, norepi, dopamine

inc risk serotonin syndrome

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12
Q

bath salts cause what Sx

A

chest pains, inc BP, pulse, agitation, hallucinations, suicidality, extreme paranoia, delusions and extreme violence

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13
Q

most commonly used drug

A

marijuana

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14
Q

other names for weed

A

pot, green, 420, reefer, joint, blunt, dope, bud, mary jane

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15
Q

Sx of marijuana

A

euphoria, inc appetite, sense of relaxation

tachycardia, injected conjunctiva, dry mouth, paranoia, distored perceptions, difficulty with memory or complex tasks

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16
Q

what are the synthetic cannabinoids

A

spice, K2, fake week

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17
Q

how is synthetic weed taken

A

smoked or used as herbal infusion in drink

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18
Q

Sx synthetic week

A

anxiety and or psychosis

inc HR, BP vomiting, pulmonary irritation

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19
Q

names for cocaine

A

blow
snow
coke
“crack” when in powder

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20
Q

what is speedball

A

cocaine and heroin mixture

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21
Q

Sx of cocaine use

A

psychomotor agitaiton, dilated pupils
inc BP HR energy speech, euphoria, sinus problems, chest pain, risk of HIV or hepatitis transmission: MI through vasoconstriction

22
Q

molecular level effects of cocaine

A

surge of dopamine release then depletion causing depression accompanied by hyperinsomnia

23
Q

Psilocybin

A

magic mushrooms, shrooms, shroomies

24
Q

how are shrooms taken

A

swallowed or used in tea

25
Q

effects of shrooms

A

distoreted perceptions, dilate pupils, hallucinations, cholinergic excess, inc BP HR Temp, anxiety, nausea

26
Q

LSD

A

tablets capsules, liquid or absorbent paper

8-12 hrs

27
Q

effects of LSD

A

vivid hallucinations and distorts reality

can cause inc BP HR temp and insomnia

28
Q

other names for ecstasy

A

MDMA, X, XTC, love drug, Molly, Adam, rave drug

29
Q

how is X taken

A

orally

inc serotonin release, inc risk serotonin syndrome

30
Q

effects of X

A

intense mental stimulation, emotional warmth, energy, disrupt temp homeostasis, nausea, chills, muscle cramps, teeth clenching, inc HR BP, pupillary dilation

31
Q

neurotoxic effect X

A

destruction serotonergic neurons

lead to long term depression

32
Q

what inhalants are abused

A

whippets, snappers
products of glue etc
huffing bagging or direct inhalation

33
Q

effects of inhalants

A

rapid high, resemble EtOH intoxication

inhaling greater quantities can result in feelings of sensation loss and or consciousness

34
Q

risks with inhalants

A

kidney failure, suffocation, hearing loss, limb spasms, bone marrow damage, organ damage or death
can cause severe CNS damage, demyelination, atrophy and degeneration

35
Q

other names for PCP

A

angel dust, wet, embalming fluid, sherms, ozone, wack

“Sernyl”

36
Q

how is PCP taken

A

smoked, swallowed snorted

37
Q

effects PCP

A

mimics schizophrenia like psychosis (NMDA antagonist)
dissociation and detachment, inc BP/HR, nystagmus, sensation of heat, unusual strength, anesthetic efx, volatility and unpredictability,

38
Q

names for ketamine

A

special K, vit K, jet, cat tranquilizer

39
Q

how is ketamine taken

A

snorted ingested, IM

40
Q

Sx of ketamine

A

inc dreams, ataxia, dec sensations, emotional warmth, epiphanies, hallucinations, near death experiences, blackouts

41
Q

other names for benzos

A

bennies, xannies, anxiety pills

42
Q

abuse of benzos causes

A

sedation, lethargy, memory problems ,ataxia, slurred speech

43
Q

chronic benzo use leads to

A

upregulation NMDA R
downregulation GABA R
CNS hyperactivity in withdrawal
risk of seixure

44
Q

what drug can precipitate severe withdrawal of benzos

A

flumazenil

45
Q

other names for barbituates

A

barbs, barbies, downers, nembies, seccies

46
Q

what happens in barbituate withdrawal

A

seizure and withdrawal Sx

47
Q

robo tripping

A

dextromethorphan DXM

dangerous with serotonin agents or anticholinergics

48
Q

what are morning glory seeds

A

mescaline

49
Q

what drugs dec seizure threshold

A

antipsychotics

50
Q

do you give benzo to alcoholic

A

no