Pharm 9-11

Question 1

black patients with hypertension medications

Answer 1

CCB or thiazide

Question 2

patient with hypertension and DM medications

Answer 2

thiazide or ACE or ARB

Question 3

pregnant people with hypertension

Answer 3

• no ACE or ARB

- methyldopa, lobetalol, nifedipine, hydralazine

Question 4

post MI

Answer 4

beta blocker or thiazide

Question 5

ACE, CCB, thiazide with edema in legs

Answer 5

amlodipine - reduce dose

Question 6

decreased HR, increased BP

Answer 6

ace or arb or ccb

Question 7

kidneys - renin

Answer 7

beta-adrenergic receptor antagonists

Question 8

angiotensinogen to angiotensin I

Answer 8

aliskirin

Question 9

angiotensin I to angiotensin II and bradykinin to inactive products

Answer 9

ACE inhibitors

Question 10

angiotensin II to adrenal cortex and/or arterioles

Answer 10

angiotensin receptor inhibitors

Question 11

reflex tachycardia side effects

Answer 11

• DHP CCB
• nitrates
• hydralazine and minoxidil (vasodilators)
• alpha-1 antagonist

Question 12

high dose of medications and not responding

Answer 12

• adherence
• add medication
• call pharmacist to see what meds/ supplements they are on and if they are refilling their medication
• diet

Question 13

hypertension urgency

Answer 13

• not taking medications

- due to side effects

Question 14

anti arrhythmic - rate

Answer 14

elderly, V. arrthmias

• beta-blockers
• calcium channel blockers
• sotalol
• dig

Question 15

anti-arrhythmic - rhythm

Answer 15

• young, severe symptoms, hypotension

- Class Ia, Ic, and III

Question 16

anti-arrhythmic drug side effect

Answer 16

dysrhythmias

Question 17

Class I (quinine, procainamide, lidocaine)
phase of AP

Answer 17

phase 0 - depolarization

Question 18

Class II Beta-blockers and Class IV Calcium Channel blockers

phase of AP

Answer 18

phase 2 - contraction

Question 19

Class III (amiodorone and bretylium)
phase of AP

Answer 19

phase 3 - repolaraziation

Question 20

Class Ia

increase or decrease AP

Answer 20

increase

Question 21

Class Ib

increase or decrease AP

Answer 21

decrease

Question 22

Class Ic

increase or decrease AP

Answer 22

no effect

Question 23

Class III

increase or decrease AP

Answer 23

increase

Question 24

afib and no other drugs are working

Answer 24

Digitals

Question 25

side effects of nitro

Answer 25

headache, don't use with erectile dysfunction medications, hypotension

Question 26

advantages of DOCAs over warfarin

Answer 26

- no need for routine lab tests - not affected by food or activity level - very few drug interactions - rapid onset and short washout for procedure - cause less catastrophic inter cranial hemorrhage

Question 27

disadvantages of DOACs over warfarin

Answer 27

- cost - twice daily - adherence is critically important - only dabigatran has an effective rapid reversal agent - not effective for stroke prevention in patients with prosthetic heart valves - lack of lab test to verify dose appropriate for size/clearance

Question 28

drug therapy for TB | rifampin - effects warfarin

Answer 28

induces warfarin clearance -recheck INR

Question 29

clotting factors for warfain

Answer 29

10,9,7,2

Question 30

stroke or MI

Answer 30

fibrolytics within 12 for MI and 3-4.5 hours for nonhemorrhagic stroke

Question 31

vWD

Answer 31

desmopressin

Question 32

170 minute stroke treatment

Answer 32

t-PA fibrolytic

Question 33

DVT pregnancy

Answer 33

- dont use heparin | - use anoxipron - LMWH

Question 34

adjusting for elevated INR | <4.5

Answer 34

skip 1 dose

Question 35

adjusting for elevated INR | 4.5-10

Answer 35

skip 2 doses

Question 36

adjusting for elevated INR | >10

Answer 36

give vitamin K

Question 37

black people heart failure

Answer 37

hydralazine and nitrate (isobo)