PHARM 1 ANS Flashcards
Neurotransmitters of the ANS
ACh
NE
E
DA
CO-transmitters
Cholinergic neurotransmission
review
Acetylcholine receptors
know mainly M2/3
Adrenergic Neurotransmission
Refers to what type of neurotransmission?
synthesis of catecholamines?
Storage of catecholamines?
release of catecholamines?
Adrenergic neurotransmission
binding of catecholamines to adrenergic receptors?
termination of catecholamine signaling?
what prevents storage of catecholamines?
What prevents reuptake of NE?
- Reserpine inhibits VMAT-2 and leads to depletion of catecholamines from sympathetic nerve endings
- Cocaine
Alpha-adrenergic receptors
a1?
a2?
beta-andrenergic receptors
b1
b2
b3
DA receptors
Direct effects of autonomic nerve stimulation
a1?
b2?
Muscarinic receptors
Modulation of vascular responses by EDRF
smooth muscle is innervated by what?
how does relaxation occur?
baroreceptor reflex
increased bp?
decreased bp?
histamine would be what?