Phagocytosis

Question 1

What is phagocytosis?

Answer 1

Cell eating microorganisms, other cells + nutrients

Question 2

What type of immune system is phagocytosis part of?

Answer 2

Innate immune system

Question 3

What is role of phagocytosis?

Answer 3

Protection from pathogens, disposal of damaged/dying (apoptotic cells), processing + presentation of antigens (Ag) => activation of adaptive immune system

Question 4

What are phagocytes?

Answer 4

Neutrophils, macrophages + dendritic cells

Question 5

What WBC is macrophage derived from?

Answer 5

Monocytes

Question 6

What do monocytes differentiate into?

Answer 6

Macrophages

Question 7

What are do dendritic cells do?

Answer 7

Form network in order to detect pathogens that can eventually try to gain access into tissues
Capture microbes, involved in phagocytosis, not just eliminate, presents antigen to T cells

Question 8

Where is dendritic cells found ?

Answer 8

In skin, mucosa and tissues

Question 9

What are 3 signals that activate T cells?

Answer 9

Antigen recognition
Co stimulation
Cytokines

Question 10

What are steps of phagocytosis?

Answer 10

Chemotaxis
Recognition + attachment to microbe/dead cells
Engulfment
Killing /digestion of ingested microbe/dead cells