peripheral nervous system Flashcards
1
Q
what are the 3 different types of synapses
A
axoaxonic synapse
synap;she’s made by one neurone onto th synapse of another neurone
axodendritic synapse
synapses that one neurone makes onto the dendrite of another neurone
axosomatic synapse
- synapses that are made onto the soma or cell body of a neurone
2
Q
what is the process of synaptic transmission
A
- action potential invades the pre synaptic terminal
- depolarisation opens Ca2+ channels
- Ca2+ rise triggers vesicles
- transmitters diffuse across synaptic cleft to post synaptic receptors
- nicotinic ach receptors activation depolarises the membrane
- post synaptic potential triggers an action potential
- signalling is turned of by transmitter removal ( acetylcholineestrase)
3
Q
how do neutroansmitters become inactive
A
- 3 processes
- metabolised extracellularly - the neutrotransmitter is broken down
- it is taken up post or presynaptically - where it may be metabolised intracellularly
- diffuses away from synaptic cleft - so no effect on the post synaptic receptors
4
Q
what are the neurotransmitter classes
A
- acetylcholine
- monoamines ( noradrenaline + dopamine)
- amino acids ( glutamate + GABA)
- neuropeptides ( short peptides modulatory transmitters)