Peptidoglycan synthesis

Question 1

Give 2 examples of carrier molecules

Answer 1

uridine diphosphate (UDP) and bactoprenol phoshpate

Question 2

What is fn of uridine diphosphate (UDP)

Answer 2

a nucleoside diphoshate used for assembly of peptidoglycan subunits

Question 3

Where is UDP uridnine diphoshate located

Answer 3

cytoplasm

Question 4

What is structure of bactoprenol phosphate

Answer 4

55 carbon lipid with a phosphate at one end

Question 5

Where is the hydrocarbon portion of bactoprenol phosphate located

Answer 5

in the PM

Question 6

Where is the phosphate portion of bactoprenol phosphate located

Answer 6

is hydrophilic and is located on the inner surface of PM

Question 7

What is the fn of bactoprenol phosphate

Answer 7

peptidoglycan subunits and a second phosphate are attached and bactoprenol phosphate moves this through PM

Question 8

What are the fn of autolysins

Answer 8

groups of periplasmic enzymes that break covalent bond btwen NAM and NEG in the glycan chain or break peptide cross links in existing peptidoglycan

Question 9

What is the purpose of autolysins

Answer 9

enables cell to add new subunits to peptidoglycan and cell gets larger