Peptic ulcers Flashcards
1
Q
PU definition
A
Defect in lining
2
Q
Most common PU
A
Gastric
3
Q
Duodenal ulcers most common after …
A
Pyloric sphincter
4
Q
Epigastric pain due to … ulcers is increased during eating
A
Gastric
5
Q
Epigastric pain due to … ulcers decrease during eating
A
Duodenal
6
Q
Medical RFs for PU
A
- h pylori
- Crohn’s disease
- zollinger Ellison syndrome (tumour)
7
Q
What molecule is released ectopically in ZE syndrome which stimulates HCL production (— pH)
A
Gastrin
8
Q
Drug RFs for PU (SANSB)
A
- SSRIs
- anticoagulants
- NSAIDs
- steroids
- bisphosphonates
9
Q
How does urea breath test detect H pylori
A
- break down C13 —> C12 + ammonia
- compare C12:C13 in CO2
10
Q
FBC in ulcers show
A
Anaemia
11
Q
In rapid urease test, what is incubated
A
biopsy + pH indicator + urea
12
Q
How does H pylori increase pH in rapid urease test
A
Produce urease —> breaks urea intro ammonia
13
Q
Bleeding in PU leads to
A
- anaemia
- shock
14
Q
Perforation in PU leads to
A
Peritonitis
15
Q
Pyloric stenosis in PU is characterised
A
- oedema/scarring surrounding pyloric sphincter
- projectile vomiting
