Hepatitis Flashcards

1
Q

Systemic symptoms of hepatitis

A
  • N/V
  • jaundice
  • muscle/joint pain
  • fever
  • loss of appetite
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2
Q

Urine changes in hepatitis

A

Darker

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3
Q

Stool colour changes in hepatitis

A

Pale

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4
Q

Pain location in hepatitis

A

Right upper quadrant

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5
Q

Hep A and D is found in

A

Stool

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6
Q

Hep B is found in

A

Blood/semen

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7
Q

Hep C is found in

A

Blood

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8
Q

Hep E is found in

A

Raw mEEt

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9
Q

HAV antibodies

A
  • IgM

- IgG

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10
Q

LFT in hepatitis

A
  • raise AST
  • raised ALT
  • raised ALP (less of a rise)
  • raised bilirubin
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11
Q

Most common hep worldwide that is not too common in UK

A

Hep A

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12
Q

fAEco-oral hep viruses

A

Hep A & E

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13
Q

Hep A extra presentations

A
  • cholestasis

- moderate hepatomegaly

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14
Q

Hep A is self limiting within how many months

A

1-3

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15
Q

Mx Hep A

A

Basic analgesia

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16
Q

Notifiable Hep viruses

A

All

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17
Q

Hep viruses that have vaccinations

A

A & B

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18
Q

Which hep virus is the ONLY DNA virus

A

B

19
Q

Transmission of hep B

A
  • direct contact (blood/bodily fluids)

- vertical transmission

20
Q

Recovery period from hep B

A

1-2 months

21
Q

How many chronic hep patients carry B

A

10%

22
Q

How many spaced out doses of hep B vaccine are given

A

3

23
Q

Summarise management algorithm for hep viruses

A
  • low screening threshold
  • screen for other viruses
  • refer to specialist
  • notify public health
  • stop smoking/alcohol
  • educate
  • fibroscan/USS
  • antivirals
  • transplantation
24
Q

Fibroscan detects

A

Cirrhosis

25
Q

USS detects

A

Heptocellular carcinoma

26
Q

Visit hep B diagram

A

To make sure u understand Abs and Ags

27
Q

Presence of surface antibody (HBsAb) indicates (2)

A
  • vaccination

- infection

28
Q

Presence of HBeAb indicates (released during replication)

A

Been thru active phase

+ HBeAb —> + infective

29
Q

Presence of HBcAb and high IgM indicate

A

Active infection

30
Q

Presence of HBcAb and low IgM indicate

A

Chronic inflammation

31
Q

Presence of HBcAb and IgG indicate

A

Past infections

32
Q

Hep C transmission

A
  • blood

- bodily fluids

33
Q

Cure for hep C

A

Direct acting antivirals

34
Q

Full recovery in hep C

A

1 in 4

35
Q

Which antigen on which hep does hep D attach to

A

HBsAg

36
Q

Hep D tx

A

None

37
Q

Why are female in 40s/50 vulnerable to type 1 autoimmune hepatitis

A

Menopause

38
Q

More severe autoimmune hepatitis

A

Type 2

39
Q

Epi type 2 hepatitis

A

Children

40
Q

Type 1 autoimmune hepatitis Abs

A
  • ANA
  • anti-actin
  • anti-SLA/LA
41
Q

Type 2 autoimmune hepatitis Abs

A
  • Anti-LKM1 (liver, kidney, microsome

- Anti- LC1 (liver, cytosol)

42
Q

1st line for autoimmune hepatitis

A

Prednisolone

43
Q

2nd line for autoimmune hepatitis

A

Azathioprine

44
Q

antibodies found in autoimmune hepatitis

A

anti smooth muscle antibodies