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Y3 GI Conditions > Colorectal cancer > Flashcards

Colorectal cancer Flashcards

1
Q

Type of cancer in colorectal cancer

A

Adenocarcinoma

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2
Q

Symptoms of LHS cancer

A
  • bleeding PR
  • mass PR
  • altered bowels
  • tenesmus
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3
Q

Symptoms of RHS cancer

A
  • — weight
  • — Hb
  • abdo pain
  • tired
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4
Q

Genes associated with colorectal cancer

A
  • KRAS
  • P53
  • FAP
  • HNPCC (lynch)
  • APC
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5
Q

Infection of what bacteria is a RF for colorectal cancer

A

Strep bovis

Other RFs typical for bowel disease

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6
Q

Criteria for 2-week referral for >40

A
  • abdo pain

- unexplained weight loss

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7
Q

Criteria for 2-week referral for >50

A

Unexplained rectal bleeding

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8
Q

Criteria for 2-week referral for >60

A

Change of bowel habits

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9
Q

2-week referral is always recommended in what deficiency

A

Iron deficiency

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10
Q

genetic patterns of FAP & HNPCC

A

AD

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11
Q

How does FAP show as

A

Adenoma along large intestines

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12
Q

Lynch syndrome is a mutation in

A

MMR

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13
Q

Even though it increases the risk of cancer, does HNPCC form adenoma

A

No, cancer is independent

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14
Q

Gold standard Ix for colorectal cancer

A

Colonoscopy + biopsy

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15
Q

What is given to patients before CT colongraphy

A

Double contrast barium

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16
Q

Antigen found in bloods of colorectal cancer

A

Carciembryonic Ag (CEA)

17
Q

Colon mets travel to

A

Liver

18
Q

Rectum mets travel to

A

Lung

19
Q

How many years is colorectal cancer screened for between 60-75 yo

A

2

20
Q

There are several surgical means to remove colorectal cancer. What monoclonal Ab can be used

A

Becavizumab

21
Q

When to use Faecal Immunochemical Test (FIT)

A

If referral criteria isn’t met

22
Q

When can FIT give false results

A

Following red meat

23
Q

Syndrome characterised by difficulty in bowel movement and emptying following resection

A

Anterior resection syndrome

24
Q

Tx

A

Unable to assess size

25
Q

T1

A

Submucosa

26
Q

T2

A

Mucosa propria (muscle)

27
Q

T3

A

Sub serosa/serosa

28
Q

T4a

A

Through serosa

29
Q

T4b

A

Tissues & organs

30
Q

Nx

A

Unable to assess nodes

31
Q

N0

A

No nodal spread

32
Q

N1

A

1-3 nodes

33
Q

N2

A

> 3 nodes

34
Q

M0

A

No metastasis

35
Q

M1

A

Metastasis

Y3 GI Conditions (23 decks)

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