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1- GIT Medicine > Peptic Ulcer Dx > Flashcards

Peptic Ulcer Dx Flashcards

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1
Q

Which is more common in men ,duodenal or gastric ulcers?

A

Duodenal

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2
Q

Which is more common in women ,duodenal or gastric ulcers?

A

Gastric

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3
Q

Is mortality rate high for Peptic ulcer

A

No

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4
Q

Main location of peptic ulcers

A

Oesophagus
Stomach
Duodenum

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5
Q

Disease associated with peptic ulcer

A

Zollinger-Ellison syndrome
Meckel’s diverticulum With ectopic gastric mucosa

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6
Q

What is peptic ulcer disease

A

Breaks in the gastric and duodenal mucosa Due to the corrosive action of pepsin and hydrochloric acid

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7
Q

Symptoms of peptic ulcer disease

A

Abdominal discomfort
pain (Epigastric, does not radiate, Burning or gnawing, Temporary relief with antacids)
nausea

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8
Q

Which type of ulcer has worsening of pain When eating With patient presenting with weightloss

A

Gastric ulcer

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9
Q

Which type of ulcer has relief of pain When eating

A

Duodenal ulcers

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10
Q

Two main causes of peptic ulcer disease

A

Decreased Protective ability of mucosa
Acid hypersecretion

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11
Q

Hostile factors leading to peptic ulcer

A

Gastric acid
H pylori
NSAIDs
Pepsin

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12
Q

Protective factors that reduce chances of peptic ulcers

A

Prostaglandins
Mucus
Bicarbonate
Blood flow

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13
Q

Enzyme affected by NSAIDs

A

COX 2

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14
Q

Triad of zollinger Ellison syndrome

A

Peptic ulcer in unusual location (jéjunum )
massive gastric acid hypersecretion
Gastric producing islet cells tumor of pancreas (gastrinoma )

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15
Q

Risk factors of peptic ulcers

A

H pylori
NSAIDs
Zollinger Ellison syndrome
Hypercalcemia
Genetic factors
Smoking
Stress
Alcohol
Diet

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16
Q

Investigations

A

Barium X ray
Upper GI series
Endoscopy

17
Q

Lab test in patient with recurrent peptic ulcer

A

Serum gastrin ,Serum calcium - gastrinoma
Histology biopsy of gastric antrum during endoscopy - h . Pylori

Urea Breath tests - h. Pylori
Serologic Elisa for h. Pylori
Stool antigen testing for h pylori

18
Q

Most accurate method to diagnose h pylori

A

Endoscopic biopsy

19
Q

Treatment

A

Antacids - H2 antagonists , PPI
Mucosal protection - prostaglandins, sulcrafate
Antibiotics - h pylori

20
Q

Complications of ulcers

A

Perforation
Penetration
Hemorrhage
GOO

21
Q

Most common complication of ulcer

A

Hemorrhage

22
Q

Percentage of ulcer hemorrhage that resolve alone

A

75-80%

23
Q

Percentage of perforation

A

5-10%

24
Q

Two forms of perforation

A

Free perforation leading to acute abdomen
Contained perforation

25
Q

Symptoms of perforation

A

Severe abdominal pain
Epigastrium pain worse
Nausea
Vomiting
Acute illness

26
Q

Most common site of penetration

A

Pancreas

27
Q

Type of ulcer that lead to GOO

A

Duodenal ulcers

28
Q

GOO symptoms

A

Nausea
vomiting
Epigastric pain
Epigastric Fullness

1- GIT Medicine (20 decks)

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