Malabsorption Syndrome

Question 1

Définition of malabsorption syndrome

Answer 1

State of abnormality in absorption of food nutrients across GIT which can involve single or multiple nutrients

Question 2

The three faces of digestion and nutrient absorption in which abnormalities could lead to malabsorption

Answer 2

Intraluminal phase
mucosal phase
post absorptive phase

Question 3

Common abnormalities happening in the intraluminal face

Answer 3

Pancreatic insufficiency in pancreatitis and pancreatic resection

hyper secretion of gastric juice in zollinger ellison syndrome

impaired bile acid synthesis and flow

Question 4

Consequence of pancreatic insufficiency

Answer 4

Deficiency of pancreatic enzymes leading to malabsorption of lipids proteins and carbohydrates

Question 5

Sequence of bile acid synthesis impairments

Answer 5

Malabsorption of fats

Question 6

Disease leading to abnormalities of the mucosa with reduced surface area for absorption

Answer 6

Celiac sprue
Whipples disease
bacterial overgrowth
infections
chemotherapy
radiation therapy

Question 7

Most common presentation of malabsorption syndrome

Answer 7

Diarrhea
weight loss
constipation
bloating
flatulence

Question 8

In which two categories can you divide clinical features of malabsorption syndrome

Answer 8

Extra intestinal
intra-intestinal or

Question 9

symptoms of intra-intestinal malabsorption

Answer 9

Diarrhea
flatulence
abdominal discomfort
steatorrhea
bloating

Question 10

Terms of extra intestinal malabsorption

Answer 10

Weight loss
anemia
fatigue
pellagra
edema

Question 11

What is the pathophysiology explanation behind flatulence and abdominal distention

Answer 11

Bacterial production of gas from carbohydrates in the colon