Gastritis Flashcards
Types of gastritis
Acute gastritis
Chronic gastritis due to H. pylori
Autoimmune chronic gastritis
Ménétrier’s dx

Main causes of acute gastritis
Alcohol
Aspirin or NSAIDS
Histology of acute gastritis
Erosion
hemorrhage
Main inflammatory cells Involved in acute gastritis
Neutrophils
Main clinical features of acute gastritis
Dyspepsia
Anorexia
Nausea
Vomiting
Hematemesis or melena
Investigation in acute gastritis
No investigation necessary in general
Biopsy or endoscopy to exclude, peptic ulcer, or cancer
Treatment of acute gastritis
Antacids
Acid suppression with PPIs , prokinetics domperidone , antiemetic metoclopramide
Most common cause of chronic gastritis
H. pylori infection
Predominant inflammatory cells in clinic gastritis with H. pylori
Lymphocytes and plasma cells
Clinical features of chronic gastritis in H. pylori infection
Generally asymptomatic
Management of chronic gastritis with H. pylori
No treatment required, but if dyspepsia should consider H. pylori eradication
Part of the stomach affected by autoimmune chronic gastritis
Body of stomach
Cells damaged in auto immune chronic gastritis
Parietal cells
Histology of autoimmune chronic gastritis
Diffuse chronic inflammation,
atrophy,
loss of fundic glands
Intestinal metaplasia sometimes hyperplasia of enterochromaffin like cells
Complication of auto immune chronic gastritis
Pernicious anemia