Gastritis Flashcards

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1
Q

Types of gastritis

A

Acute gastritis
Chronic gastritis due to H. pylori
Autoimmune chronic gastritis
Ménétrier’s dx

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2
Q

Main causes of acute gastritis

A

Alcohol
Aspirin or NSAIDS

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3
Q

Histology of acute gastritis

A

Erosion
hemorrhage

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4
Q

Main inflammatory cells Involved in acute gastritis

A

Neutrophils

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5
Q

Main clinical features of acute gastritis

A

Dyspepsia
Anorexia
Nausea
Vomiting
Hematemesis or melena

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6
Q

Investigation in acute gastritis

A

No investigation necessary in general
Biopsy or endoscopy to exclude, peptic ulcer, or cancer

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7
Q

Treatment of acute gastritis

A

Antacids
Acid suppression with PPIs , prokinetics domperidone , antiemetic metoclopramide

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8
Q

Most common cause of chronic gastritis

A

H. pylori infection

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9
Q

Predominant inflammatory cells in clinic gastritis with H. pylori

A

Lymphocytes and plasma cells

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10
Q

Clinical features of chronic gastritis in H. pylori infection

A

Generally asymptomatic

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11
Q

Management of chronic gastritis with H. pylori

A

No treatment required, but if dyspepsia should consider H. pylori eradication

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12
Q

Part of the stomach affected by autoimmune chronic gastritis

A

Body of stomach

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13
Q

Cells damaged in auto immune chronic gastritis

A

Parietal cells

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14
Q

Histology of autoimmune chronic gastritis

A

Diffuse chronic inflammation,
atrophy,
loss of fundic glands
Intestinal metaplasia sometimes hyperplasia of enterochromaffin like cells

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15
Q

Complication of auto immune chronic gastritis

A

Pernicious anemia

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16
Q

Risk of gastric cancer in auto immune, chronic gastritis

A

2 to 3 fold increase

17
Q

What is ménétrier dx

A

Elongated and tortuous gastric pits with replacement of Parietal and chief cells by mucus secreting cells

18
Q

Clinical features of ménétrier dx

A

Hypochlorridria
, upper G.I. symptoms
Protein losing enteropathy

19
Q

Treatment ménétrier dx

A

PPIs, H. pylori eradication partial gastrectomy