Peptic Ulcer

Question 1

Classification of peptic ulcer

Answer 1

Acid suppressants
• Reduces HCl production from parietal cells
• Given on continuous basis (round the clock protection)
• PPI
• H2 blockers
• Antimuscarinic
• Prostaglandins E1 (misoprostol)

Acid neutralizers
• Directly neutralizes HCl in stomach lumen
• Fastest acting
• Given for prompt pain relief
Antacids

Ulcer protectives
• Sucralfate
• Bismuth compounds

H pylori Infection
Antibiotics

Miscellaneous
• Antifoaming (Alginic acid) in GERD
• Antiflatulence (Simethicone)