Anti Parkinsonism Flashcards
1
Q
Classification of anti-Parkinsonism
A
Drugs influencing brain dopaminergic system:
(a) Dopamine precursor: Levodopa (L-Dopa).
(b) Dopamine agonists: Bromocriptine, pramipexole, ropipirole.
(c) NMDA-receptor antagonist: Amantadine.
(d) Monoamine oxidase (MAO-B inhibitors: Selegiline (deprenyl), rasagiline.
(e) Catechol-O-methyltransferase (COMT) inhibitors: Tolcapone, entacapone.
2. Drugs influencing brain cholinergic system
(a) Centrally acting anticholinergic drugs: Benztropine, beykhexol (trihexyphenidyl), prc
cyclidine, biperiden.
(b) Antihistaminics (H1-blockers) with anticholinergic activity: Promethazine, diphenhyd amine, orphenadrine.
The main aim of drug therapy in parkinsonism is to either enhance dopamine
